Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
| Uniprot primary ID | P21728 |
| PDB ID | 1OZ5 |
| DrugBank ID | DB00777 DB06148 DB01063 DB01624 DB01608 DB01623 DB00246 |
| BioGrid ID | 108146 |
| GuidetoPHARMACOLOGY ID | 214 |
| PharmGKB ID | PA147 |
| KEGG ID | hsa:1812 |
| DIP ID | |
| STRING ID | 9606.ENSP00000327652 |
| IntAct ID | |
| DMDM | 118228 |
| BRENDA | |
| Reactome | R-HSA-418555 R-HSA-390651 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 1812 |
| BindingDB | P21728 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.590 | 0.000 | 0.930 | 0.005 | 0.760 | 0.000 | 0.710 | 0.000 | 0.820 | 0.000 | 0.557 | 0.005 | Download |
| Estate fingerprints | 0.691 | 0.003 | 0.749 | 0.005 | 0.720 | 0.000 | 0.710 | 0.000 | 0.790 | 0.000 | 0.440 | 0.005 | Download |
| MACCS fingerprints | 0.720 | 0.000 | 0.722 | 0.003 | 0.721 | 0.003 | 0.720 | 0.000 | 0.810 | 0.000 | 0.449 | 0.003 | Download |
| Daylight fingerprints | 0.545 | 0.005 | 0.899 | 0.000 | 0.722 | 0.004 | 0.662 | 0.004 | 0.780 | 0.000 | 0.479 | 0.006 | Download |
| ECFP2 fingerprints | 0.769 | 0.006 | 0.851 | 0.003 | 0.810 | 0.000 | 0.800 | 0.000 | 0.900 | 0.000 | 0.619 | 0.006 | Download |
| ECFP4 fingerprints | 0.713 | 0.005 | 0.907 | 0.000 | 0.810 | 0.000 | 0.791 | 0.003 | 0.910 | 0.000 | 0.636 | 0.005 | Download |
| ECFP6 fingerprints | 0.668 | 0.004 | 0.932 | 0.005 | 0.800 | 0.000 | 0.770 | 0.000 | 0.900 | 0.000 | 0.620 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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