Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
| Uniprot primary ID | P21918 |
| PDB ID | |
| DrugBank ID | DB06148 DB01238 DB01235 DB01624 DB00568 DB00408 DB00370 |
| BioGrid ID | 108150 |
| GuidetoPHARMACOLOGY ID | 218 |
| PharmGKB ID | PA148 |
| KEGG ID | hsa:1816 |
| DIP ID | |
| STRING ID | 9606.ENSP00000306129 |
| IntAct ID | |
| DMDM | 118214 |
| BRENDA | |
| Reactome | R-HSA-418555 R-HSA-390651 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 1816 |
| BindingDB | P21918 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.612 | 0.006 | 0.768 | 0.005 | 0.690 | 0.005 | 0.663 | 0.005 | 0.781 | 0.003 | 0.383 | 0.008 | Download |
| Estate fingerprints | 0.668 | 0.004 | 0.740 | 0.008 | 0.704 | 0.007 | 0.693 | 0.007 | 0.779 | 0.003 | 0.405 | 0.013 | Download |
| MACCS fingerprints | 0.678 | 0.006 | 0.778 | 0.003 | 0.728 | 0.004 | 0.715 | 0.005 | 0.790 | 0.000 | 0.461 | 0.007 | Download |
| Daylight fingerprints | 0.578 | 0.006 | 0.772 | 0.003 | 0.675 | 0.005 | 0.638 | 0.004 | 0.710 | 0.000 | 0.354 | 0.007 | Download |
| ECFP2 fingerprints | 0.743 | 0.005 | 0.801 | 0.008 | 0.772 | 0.004 | 0.766 | 0.007 | 0.872 | 0.004 | 0.547 | 0.012 | Download |
| ECFP4 fingerprints | 0.750 | 0.007 | 0.848 | 0.007 | 0.799 | 0.006 | 0.789 | 0.006 | 0.900 | 0.000 | 0.604 | 0.010 | Download |
| ECFP6 fingerprints | 0.675 | 0.005 | 0.881 | 0.009 | 0.778 | 0.004 | 0.756 | 0.005 | 0.879 | 0.003 | 0.574 | 0.008 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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