TargetNet
  Target name

P21918: D(1B) dopamine receptor

  Protein function

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

  Database links
Uniprot primary ID P21918
PDB ID
DrugBank ID DB06148 DB01238 DB01235 DB01624 DB00568 DB00408 DB00370
BioGrid ID 108150
GuidetoPHARMACOLOGY ID 218
PharmGKB ID PA148
KEGG ID hsa:1816
DIP ID
STRING ID 9606.ENSP00000306129
IntAct ID
DMDM 118214
BRENDA
Reactome R-HSA-418555 R-HSA-390651
SignaLink
BioCyc
Entrez Gene (Gene ID) 1816
BindingDB P21918
  Model Performance Metrics
Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.612 0.006 0.768 0.005 0.690 0.005 0.663 0.005 0.781 0.003 0.383 0.008 Download
Estate fingerprints 0.668 0.004 0.740 0.008 0.704 0.007 0.693 0.007 0.779 0.003 0.405 0.013 Download
MACCS fingerprints 0.678 0.006 0.778 0.003 0.728 0.004 0.715 0.005 0.790 0.000 0.461 0.007 Download
Daylight fingerprints 0.578 0.006 0.772 0.003 0.675 0.005 0.638 0.004 0.710 0.000 0.354 0.007 Download
ECFP2 fingerprints 0.743 0.005 0.801 0.008 0.772 0.004 0.766 0.007 0.872 0.004 0.547 0.012 Download
ECFP4 fingerprints 0.750 0.007 0.848 0.007 0.799 0.006 0.789 0.006 0.900 0.000 0.604 0.010 Download
ECFP6 fingerprints 0.675 0.005 0.881 0.009 0.778 0.004 0.756 0.005 0.879 0.003 0.574 0.008 Download
  Download datasets
Positive dataset Negative dataset

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 E-mail: biomed@csu.edu.cn