Target name

P21918: D(1B) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P21918
PDB ID
DrugBank ID DB06148 DB01238 DB01235 DB01624 DB00568 DB00408 DB00370
BioGrid ID 108150
GuidetoPHARMACOLOGY ID 218
PharmGKB ID PA148
KEGG ID hsa:1816
DIP ID
STRING ID 9606.ENSP00000306129
IntAct ID
DMDM 118214
BRENDA
Reactome R-HSA-418555 R-HSA-390651
SignaLink
BioCyc
Entrez Gene (Gene ID) 1816
BindingDB P21918

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.612 0.006 0.768 0.005 0.690 0.005 0.663 0.005 0.781 0.003 0.383 0.008 Download
Estate fingerprints 0.668 0.004 0.740 0.008 0.704 0.007 0.693 0.007 0.779 0.003 0.405 0.013 Download
MACCS fingerprints 0.678 0.006 0.778 0.003 0.728 0.004 0.715 0.005 0.790 0.000 0.461 0.007 Download
Daylight fingerprints 0.578 0.006 0.772 0.003 0.675 0.005 0.638 0.004 0.710 0.000 0.354 0.007 Download
ECFP2 fingerprints 0.743 0.005 0.801 0.008 0.772 0.004 0.766 0.007 0.872 0.004 0.547 0.012 Download
ECFP4 fingerprints 0.750 0.007 0.848 0.007 0.799 0.006 0.789 0.006 0.900 0.000 0.604 0.010 Download
ECFP6 fingerprints 0.675 0.005 0.881 0.009 0.778 0.004 0.756 0.005 0.879 0.003 0.574 0.008 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn