Target name

P21980: Protein-glutamine gamma-glutamyltransferase 2


  Protein function

Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.

  Database links

Uniprot primary ID P21980
PDB ID 3LY6 3S3J 1FAU 2Q3Z 1KV3 3S3S 3S3P 4PYG
DrugBank ID DB00130
BioGrid ID 112910
GuidetoPHARMACOLOGY ID
PharmGKB ID PA36491
KEGG ID hsa:7052
DIP ID DIP-33557N
STRING ID 9606.ENSP00000355330
IntAct ID P21980
DMDM 20141877
BRENDA 2.3.2.13
Reactome
SignaLink P21980
BioCyc
Entrez Gene (Gene ID) 7052
BindingDB P21980

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.954 0.007 0.958 0.000 0.956 0.005 0.956 0.005 0.980 0.000 0.908 0.006 Download
Estate fingerprints 0.835 0.007 0.915 0.005 0.875 0.005 0.873 0.005 0.960 0.000 0.757 0.008 Download
MACCS fingerprints 0.723 0.007 0.901 0.005 0.812 0.006 0.792 0.006 0.928 0.004 0.630 0.008 Download
Daylight fingerprints 0.863 0.009 0.977 0.005 0.920 0.005 0.914 0.007 0.968 0.004 0.845 0.008 Download
ECFP2 fingerprints 0.960 0.000 0.962 0.003 0.961 0.003 0.961 0.003 0.980 0.000 0.928 0.004 Download
ECFP4 fingerprints 0.960 0.000 0.980 0.007 0.970 0.005 0.969 0.003 0.980 0.000 0.944 0.007 Download
ECFP6 fingerprints 0.960 0.000 0.998 0.005 0.979 0.003 0.976 0.005 0.987 0.005 0.956 0.005 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn