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E-mail: biomed@csu.edu.cn
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Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
| Uniprot primary ID | P22303 |
| PDB ID | 1B41 2X8B 1F8U 4EY4 1PUV 1PUW 4M0E 4BDT 4M0F 3LII 4EY5 1VZJ 2CLJ 4EY6 4EY8 4PQE 4EY7 |
| DrugBank ID | DB00843 DB00944 DB00981 DB01364 DB00733 DB08996 DB00545 |
| BioGrid ID | 106561 |
| GuidetoPHARMACOLOGY ID | 2465 |
| PharmGKB ID | PA20 |
| KEGG ID | hsa:43 |
| DIP ID | DIP-1119N |
| STRING ID | 9606.ENSP00000303211 |
| IntAct ID | P22303 |
| DMDM | 113037 |
| BRENDA | 3.1.1.7 |
| Reactome | R-HSA-112311 R-HSA-1483191 R-HSA-422085 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 43 |
| BindingDB | P22303 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.840 | 0.000 | 0.840 | 0.000 | 0.840 | 0.000 | 0.840 | 0.000 | 0.910 | 0.000 | 0.678 | 0.004 | Download |
| Estate fingerprints | 0.779 | 0.003 | 0.729 | 0.005 | 0.754 | 0.005 | 0.758 | 0.004 | 0.820 | 0.000 | 0.508 | 0.006 | Download |
| MACCS fingerprints | 0.850 | 0.000 | 0.710 | 0.000 | 0.780 | 0.000 | 0.790 | 0.000 | 0.860 | 0.000 | 0.566 | 0.005 | Download |
| Daylight fingerprints | 0.750 | 0.000 | 0.790 | 0.000 | 0.770 | 0.000 | 0.760 | 0.000 | 0.806 | 0.005 | 0.539 | 0.003 | Download |
| ECFP2 fingerprints | 0.930 | 0.000 | 0.902 | 0.000 | 0.916 | 0.005 | 0.918 | 0.004 | 0.970 | 0.000 | 0.832 | 0.004 | Download |
| ECFP4 fingerprints | 0.901 | 0.003 | 0.959 | 0.000 | 0.930 | 0.000 | 0.924 | 0.005 | 0.980 | 0.000 | 0.858 | 0.004 | Download |
| ECFP6 fingerprints | 0.841 | 0.003 | 0.979 | 0.003 | 0.910 | 0.000 | 0.900 | 0.000 | 0.980 | 0.000 | 0.823 | 0.005 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: biomed@csu.edu.cn
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