Can degrade fibrillar type I, II, and III collagens.
| Uniprot primary ID | P22894 |
| PDB ID | 2OY2 2OY4 3DNG 1JAP 1JAQ 1JAN 1JAO 1A86 1I76 4QKZ 1A85 1I73 1ZS0 1ZVX 1JH1 1JJ9 1MMB 1ZP5 3DPE 3DPF 1KBC 3TT4 1BZS 1MNC |
| DrugBank ID | DB00786 |
| BioGrid ID | 110460 |
| GuidetoPHARMACOLOGY ID | 1632 |
| PharmGKB ID | PA30888 |
| KEGG ID | hsa:4317 |
| DIP ID | |
| STRING ID | 9606.ENSP00000236826 |
| IntAct ID | |
| DMDM | 116862 |
| BRENDA | 3.4.24.34 |
| Reactome | R-HSA-1592389 R-HSA-1474228 R-HSA-1442490 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 4317 |
| BindingDB | P22894 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.932 | 0.004 | 0.908 | 0.000 | 0.920 | 0.000 | 0.920 | 0.000 | 0.970 | 0.000 | 0.843 | 0.005 | Download |
| Estate fingerprints | 0.910 | 0.000 | 0.848 | 0.004 | 0.879 | 0.003 | 0.880 | 0.000 | 0.950 | 0.000 | 0.759 | 0.003 | Download |
| MACCS fingerprints | 0.909 | 0.003 | 0.871 | 0.003 | 0.890 | 0.000 | 0.890 | 0.000 | 0.960 | 0.000 | 0.780 | 0.000 | Download |
| Daylight fingerprints | 0.762 | 0.004 | 0.940 | 0.000 | 0.851 | 0.003 | 0.840 | 0.000 | 0.950 | 0.000 | 0.714 | 0.005 | Download |
| ECFP2 fingerprints | 0.964 | 0.005 | 0.922 | 0.000 | 0.943 | 0.005 | 0.947 | 0.005 | 0.990 | 0.000 | 0.890 | 0.000 | Download |
| ECFP4 fingerprints | 0.969 | 0.003 | 0.949 | 0.005 | 0.959 | 0.003 | 0.960 | 0.000 | 0.990 | 0.000 | 0.918 | 0.004 | Download |
| ECFP6 fingerprints | 0.950 | 0.000 | 0.970 | 0.005 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.916 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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