Target name

P23280: Carbonic anhydrase 6


  Protein function

Reversible hydration of carbon dioxide. Its role in saliva is unknown.

  Database links

Uniprot primary ID P23280
PDB ID 3FE4
DrugBank ID DB00909 DB06795
BioGrid ID 107220
GuidetoPHARMACOLOGY ID
PharmGKB ID PA25995
KEGG ID hsa:765
DIP ID
STRING ID 9606.ENSP00000366662
IntAct ID
DMDM 116241278
BRENDA 4.2.1.1
Reactome R-HSA-1475029
SignaLink
BioCyc
Entrez Gene (Gene ID) 765
BindingDB P23280

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.941 0.012 0.875 0.007 0.908 0.009 0.910 0.009 0.966 0.005 0.815 0.016 Download
Estate fingerprints 0.850 0.008 0.872 0.007 0.861 0.003 0.861 0.003 0.940 0.000 0.726 0.007 Download
MACCS fingerprints 0.882 0.011 0.886 0.007 0.884 0.007 0.884 0.007 0.940 0.000 0.766 0.013 Download
Daylight fingerprints 0.671 0.013 0.807 0.000 0.739 0.007 0.719 0.007 0.810 0.000 0.480 0.012 Download
ECFP2 fingerprints 0.961 0.007 0.865 0.005 0.913 0.005 0.916 0.005 0.970 0.000 0.827 0.013 Download
ECFP4 fingerprints 0.969 0.006 0.851 0.009 0.910 0.007 0.916 0.005 0.972 0.004 0.825 0.010 Download
ECFP6 fingerprints 0.969 0.003 0.871 0.006 0.920 0.000 0.926 0.005 0.970 0.000 0.847 0.005 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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