Target name

P23795: Acetylcholinesterase


  Protein function

Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.

  Database links

Uniprot primary ID P23795
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID bta:540446
DIP ID
STRING ID 9913.ENSBTAP00000001517
IntAct ID
DMDM
BRENDA 3.1.1.7
Reactome R-BTA-112311 R-BTA-1483191
SignaLink
BioCyc
Entrez Gene (Gene ID) 540446
BindingDB P23795

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.802 0.008 0.958 0.005 0.880 0.005 0.870 0.005 0.957 0.005 0.768 0.010 Download
Estate fingerprints 0.837 0.005 0.741 0.010 0.789 0.009 0.798 0.004 0.849 0.003 0.579 0.012 Download
MACCS fingerprints 0.874 0.007 0.854 0.005 0.864 0.005 0.865 0.005 0.944 0.005 0.728 0.006 Download
Daylight fingerprints 0.608 0.006 0.994 0.000 0.801 0.003 0.756 0.005 0.943 0.005 0.657 0.007 Download
ECFP2 fingerprints 0.919 0.003 0.939 0.005 0.929 0.003 0.929 0.003 0.980 0.000 0.858 0.004 Download
ECFP4 fingerprints 0.893 0.007 0.973 0.003 0.933 0.005 0.929 0.003 0.990 0.000 0.869 0.007 Download
ECFP6 fingerprints 0.825 0.010 0.997 0.004 0.911 0.006 0.901 0.006 0.990 0.000 0.833 0.008 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn