Target name

P23944: Alpha-1D adrenergic receptor


  Protein function

This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

  Database links

Uniprot primary ID P23944
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 24
PharmGKB ID
KEGG ID rno:29413
DIP ID
STRING ID 10116.ENSRNOP00000028877
IntAct ID
DMDM
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 29413
BindingDB P23944

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.836 0.008 0.890 0.005 0.863 0.005 0.859 0.006 0.936 0.005 0.726 0.008 Download
Estate fingerprints 0.711 0.007 0.747 0.009 0.729 0.007 0.724 0.005 0.818 0.004 0.455 0.013 Download
MACCS fingerprints 0.839 0.003 0.731 0.007 0.785 0.005 0.798 0.004 0.870 0.000 0.575 0.008 Download
Daylight fingerprints 0.698 0.013 0.966 0.008 0.832 0.006 0.805 0.008 0.937 0.005 0.689 0.014 Download
ECFP2 fingerprints 0.872 0.006 0.910 0.003 0.891 0.006 0.889 0.006 0.960 0.000 0.782 0.006 Download
ECFP4 fingerprints 0.899 0.003 0.965 0.000 0.932 0.004 0.931 0.003 0.980 0.000 0.871 0.003 Download
ECFP6 fingerprints 0.882 0.004 0.978 0.000 0.930 0.000 0.930 0.000 0.980 0.000 0.868 0.004 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn