Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
| Uniprot primary ID | P23977 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 247007 |
| GuidetoPHARMACOLOGY ID | 927 |
| PharmGKB ID | |
| KEGG ID | rno:24898 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000047272 |
| IntAct ID | P23977 |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-442660 R-RNO-379401 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 24898 |
| BindingDB | P23977 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.900 | 0.000 | 0.880 | 0.005 | 0.890 | 0.000 | 0.891 | 0.003 | 0.953 | 0.005 | 0.790 | 0.000 | Download |
| Estate fingerprints | 0.890 | 0.000 | 0.834 | 0.000 | 0.862 | 0.004 | 0.870 | 0.000 | 0.930 | 0.000 | 0.730 | 0.000 | Download |
| MACCS fingerprints | 0.880 | 0.000 | 0.860 | 0.000 | 0.870 | 0.000 | 0.870 | 0.000 | 0.950 | 0.000 | 0.740 | 0.000 | Download |
| Daylight fingerprints | 0.820 | 0.000 | 0.820 | 0.000 | 0.820 | 0.000 | 0.820 | 0.000 | 0.860 | 0.000 | 0.631 | 0.003 | Download |
| ECFP2 fingerprints | 0.930 | 0.000 | 0.950 | 0.003 | 0.940 | 0.000 | 0.940 | 0.000 | 0.980 | 0.000 | 0.877 | 0.005 | Download |
| ECFP4 fingerprints | 0.913 | 0.005 | 0.975 | 0.005 | 0.944 | 0.005 | 0.940 | 0.000 | 0.990 | 0.000 | 0.890 | 0.000 | Download |
| ECFP6 fingerprints | 0.899 | 0.003 | 0.979 | 0.000 | 0.939 | 0.003 | 0.930 | 0.000 | 0.990 | 0.000 | 0.873 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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