Target name

P23978: Sodium- and chloride-dependent GABA transporter 1


  Protein function

Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.

  Database links

Uniprot primary ID P23978
PDB ID
DrugBank ID
BioGrid ID 249421
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID rno:79212
DIP ID
STRING ID 10116.ENSRNOP00000009705
IntAct ID
DMDM
BRENDA
Reactome R-RNO-442660 R-RNO-888593
SignaLink
BioCyc
Entrez Gene (Gene ID) 79212
BindingDB P23978

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.990 0.000 0.990 0.000 0.990 0.000 0.990 0.000 0.993 0.005 0.980 0.000 Download
Estate fingerprints 0.961 0.003 0.913 0.008 0.937 0.005 0.937 0.005 0.990 0.000 0.871 0.009 Download
MACCS fingerprints 0.970 0.000 0.990 0.003 0.980 0.000 0.980 0.000 1.000 0.000 0.961 0.003 Download
Daylight fingerprints 0.986 0.005 0.894 0.000 0.940 0.000 0.946 0.005 0.940 0.000 0.886 0.005 Download
ECFP2 fingerprints 0.965 0.005 0.985 0.000 0.975 0.005 0.975 0.005 1.000 0.000 0.955 0.005 Download
ECFP4 fingerprints 0.968 0.006 0.992 0.004 0.980 0.000 0.980 0.000 1.000 0.000 0.966 0.005 Download
ECFP6 fingerprints 0.963 0.007 0.999 0.000 0.981 0.003 0.981 0.003 1.000 0.000 0.963 0.007 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn