Target name

P25099: Adenosine receptor A1


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

  Database links

Uniprot primary ID P25099
PDB ID
DrugBank ID
BioGrid ID 247960
GuidetoPHARMACOLOGY ID 18
PharmGKB ID
KEGG ID rno:29290
DIP ID
STRING ID 10116.ENSRNOP00000004602
IntAct ID P25099
DMDM
BRENDA
Reactome R-RNO-417973 R-RNO-418594
SignaLink
BioCyc
Entrez Gene (Gene ID) 29290
BindingDB P25099

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.870 0.000 0.950 0.005 0.910 0.000 0.910 0.000 0.950 0.000 0.820 0.000 Download
Estate fingerprints 0.892 0.004 0.808 0.000 0.850 0.000 0.860 0.000 0.910 0.000 0.710 0.000 Download
MACCS fingerprints 0.875 0.005 0.825 0.000 0.850 0.000 0.855 0.005 0.920 0.000 0.704 0.005 Download
Daylight fingerprints 0.789 0.003 0.891 0.000 0.840 0.000 0.830 0.000 0.900 0.000 0.690 0.000 Download
ECFP2 fingerprints 0.920 0.000 0.940 0.000 0.930 0.000 0.930 0.000 0.980 0.000 0.860 0.000 Download
ECFP4 fingerprints 0.890 0.000 0.970 0.003 0.930 0.000 0.930 0.000 0.980 0.000 0.870 0.000 Download
ECFP6 fingerprints 0.863 0.005 0.977 0.000 0.920 0.000 0.920 0.000 0.980 0.000 0.850 0.000 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn