Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
| Uniprot primary ID | P25099 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 247960 |
| GuidetoPHARMACOLOGY ID | 18 |
| PharmGKB ID | |
| KEGG ID | rno:29290 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000004602 |
| IntAct ID | P25099 |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-417973 R-RNO-418594 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 29290 |
| BindingDB | P25099 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.870 | 0.000 | 0.950 | 0.005 | 0.910 | 0.000 | 0.910 | 0.000 | 0.950 | 0.000 | 0.820 | 0.000 | Download |
| Estate fingerprints | 0.892 | 0.004 | 0.808 | 0.000 | 0.850 | 0.000 | 0.860 | 0.000 | 0.910 | 0.000 | 0.710 | 0.000 | Download |
| MACCS fingerprints | 0.875 | 0.005 | 0.825 | 0.000 | 0.850 | 0.000 | 0.855 | 0.005 | 0.920 | 0.000 | 0.704 | 0.005 | Download |
| Daylight fingerprints | 0.789 | 0.003 | 0.891 | 0.000 | 0.840 | 0.000 | 0.830 | 0.000 | 0.900 | 0.000 | 0.690 | 0.000 | Download |
| ECFP2 fingerprints | 0.920 | 0.000 | 0.940 | 0.000 | 0.930 | 0.000 | 0.930 | 0.000 | 0.980 | 0.000 | 0.860 | 0.000 | Download |
| ECFP4 fingerprints | 0.890 | 0.000 | 0.970 | 0.003 | 0.930 | 0.000 | 0.930 | 0.000 | 0.980 | 0.000 | 0.870 | 0.000 | Download |
| ECFP6 fingerprints | 0.863 | 0.005 | 0.977 | 0.000 | 0.920 | 0.000 | 0.920 | 0.000 | 0.980 | 0.000 | 0.850 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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