Target name

P25100: Alpha-1D adrenergic receptor


  Protein function

This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

  Database links

Uniprot primary ID P25100
PDB ID
DrugBank ID DB00777 DB06148 DB00598 DB01142 DB01049 DB06207 DB00590
BioGrid ID 106656
GuidetoPHARMACOLOGY ID 24
PharmGKB ID PA24597
KEGG ID hsa:146
DIP ID
STRING ID 9606.ENSP00000368766
IntAct ID P25100
DMDM 1168243
BRENDA
Reactome R-HSA-390696 R-HSA-416476 R-HSA-416482
SignaLink
BioCyc
Entrez Gene (Gene ID) 146
BindingDB P25100

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.712 0.006 0.922 0.003 0.817 0.005 0.795 0.005 0.917 0.005 0.647 0.007 Download
Estate fingerprints 0.702 0.004 0.710 0.004 0.706 0.005 0.705 0.005 0.810 0.000 0.414 0.005 Download
MACCS fingerprints 0.777 0.005 0.763 0.005 0.770 0.000 0.772 0.004 0.850 0.000 0.542 0.004 Download
Daylight fingerprints 0.703 0.007 0.929 0.005 0.816 0.005 0.792 0.006 0.904 0.005 0.647 0.009 Download
ECFP2 fingerprints 0.882 0.004 0.930 0.000 0.906 0.005 0.904 0.005 0.970 0.000 0.813 0.005 Download
ECFP4 fingerprints 0.878 0.004 0.962 0.003 0.920 0.000 0.920 0.000 0.980 0.000 0.844 0.005 Download
ECFP6 fingerprints 0.832 0.004 0.986 0.000 0.909 0.003 0.900 0.000 0.980 0.000 0.822 0.004 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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