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E-mail: biomed@csu.edu.cn
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This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.
| Uniprot primary ID | P25100 |
| PDB ID | |
| DrugBank ID | DB00777 DB06148 DB00598 DB01142 DB01049 DB06207 DB00590 |
| BioGrid ID | 106656 |
| GuidetoPHARMACOLOGY ID | 24 |
| PharmGKB ID | PA24597 |
| KEGG ID | hsa:146 |
| DIP ID | |
| STRING ID | 9606.ENSP00000368766 |
| IntAct ID | P25100 |
| DMDM | 1168243 |
| BRENDA | |
| Reactome | R-HSA-390696 R-HSA-416476 R-HSA-416482 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 146 |
| BindingDB | P25100 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.712 | 0.006 | 0.922 | 0.003 | 0.817 | 0.005 | 0.795 | 0.005 | 0.917 | 0.005 | 0.647 | 0.007 | Download |
| Estate fingerprints | 0.702 | 0.004 | 0.710 | 0.004 | 0.706 | 0.005 | 0.705 | 0.005 | 0.810 | 0.000 | 0.414 | 0.005 | Download |
| MACCS fingerprints | 0.777 | 0.005 | 0.763 | 0.005 | 0.770 | 0.000 | 0.772 | 0.004 | 0.850 | 0.000 | 0.542 | 0.004 | Download |
| Daylight fingerprints | 0.703 | 0.007 | 0.929 | 0.005 | 0.816 | 0.005 | 0.792 | 0.006 | 0.904 | 0.005 | 0.647 | 0.009 | Download |
| ECFP2 fingerprints | 0.882 | 0.004 | 0.930 | 0.000 | 0.906 | 0.005 | 0.904 | 0.005 | 0.970 | 0.000 | 0.813 | 0.005 | Download |
| ECFP4 fingerprints | 0.878 | 0.004 | 0.962 | 0.003 | 0.920 | 0.000 | 0.920 | 0.000 | 0.980 | 0.000 | 0.844 | 0.005 | Download |
| ECFP6 fingerprints | 0.832 | 0.004 | 0.986 | 0.000 | 0.909 | 0.003 | 0.900 | 0.000 | 0.980 | 0.000 | 0.822 | 0.004 | Download |
| Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn
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