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E-mail: biomed@csu.edu.cn
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Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid.
| Uniprot primary ID | P25929 |
| PDB ID | 2F1U 2IIL |
| DrugBank ID | |
| BioGrid ID | 110946 |
| GuidetoPHARMACOLOGY ID | 305 |
| PharmGKB ID | PA258 |
| KEGG ID | hsa:4886 |
| DIP ID | |
| STRING ID | 9606.ENSP00000354652 |
| IntAct ID | P25929 |
| DMDM | 128997 |
| BRENDA | |
| Reactome | R-HSA-418594 R-HSA-375276 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 4886 |
| BindingDB | P25929 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.726 | 0.005 | 0.894 | 0.003 | 0.810 | 0.000 | 0.791 | 0.003 | 0.850 | 0.000 | 0.628 | 0.004 | Download |
| Estate fingerprints | 0.723 | 0.005 | 0.717 | 0.005 | 0.720 | 0.000 | 0.720 | 0.000 | 0.790 | 0.000 | 0.439 | 0.007 | Download |
| MACCS fingerprints | 0.774 | 0.005 | 0.736 | 0.005 | 0.755 | 0.005 | 0.760 | 0.000 | 0.817 | 0.005 | 0.508 | 0.006 | Download |
| Daylight fingerprints | 0.752 | 0.004 | 0.774 | 0.005 | 0.763 | 0.005 | 0.761 | 0.003 | 0.800 | 0.000 | 0.529 | 0.006 | Download |
| ECFP2 fingerprints | 0.767 | 0.005 | 0.913 | 0.003 | 0.840 | 0.000 | 0.829 | 0.003 | 0.897 | 0.005 | 0.690 | 0.005 | Download |
| ECFP4 fingerprints | 0.764 | 0.005 | 0.956 | 0.000 | 0.860 | 0.000 | 0.847 | 0.005 | 0.919 | 0.003 | 0.736 | 0.005 | Download |
| ECFP6 fingerprints | 0.751 | 0.003 | 0.969 | 0.004 | 0.860 | 0.000 | 0.845 | 0.005 | 0.901 | 0.003 | 0.742 | 0.004 | Download |
| Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn
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