Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.
| Uniprot primary ID | P28647 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 21 |
| PharmGKB ID | |
| KEGG ID | rno:100911796 rno:25370 |
| DIP ID | DIP-217N |
| STRING ID | 10116.ENSRNOP00000046340 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 100363178;25370;100911796 |
| BindingDB | P28647 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.830 | 0.005 | 0.988 | 0.000 | 0.909 | 0.003 | 0.901 | 0.003 | 0.968 | 0.004 | 0.830 | 0.005 | Download |
| Estate fingerprints | 0.802 | 0.008 | 0.918 | 0.004 | 0.860 | 0.005 | 0.852 | 0.008 | 0.942 | 0.004 | 0.727 | 0.011 | Download |
| MACCS fingerprints | 0.765 | 0.007 | 0.967 | 0.005 | 0.866 | 0.005 | 0.854 | 0.005 | 0.940 | 0.000 | 0.746 | 0.008 | Download |
| Daylight fingerprints | 0.831 | 0.007 | 0.977 | 0.007 | 0.904 | 0.005 | 0.897 | 0.005 | 0.950 | 0.000 | 0.819 | 0.007 | Download |
| ECFP2 fingerprints | 0.888 | 0.004 | 0.972 | 0.000 | 0.930 | 0.000 | 0.928 | 0.004 | 0.980 | 0.000 | 0.860 | 0.000 | Download |
| ECFP4 fingerprints | 0.881 | 0.009 | 0.973 | 0.000 | 0.927 | 0.005 | 0.924 | 0.005 | 0.980 | 0.000 | 0.857 | 0.005 | Download |
| ECFP6 fingerprints | 0.870 | 0.000 | 0.990 | 0.000 | 0.930 | 0.000 | 0.930 | 0.000 | 0.980 | 0.000 | 0.870 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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