Target name

P28647: Adenosine receptor A3


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction.

  Database links

Uniprot primary ID P28647
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 21
PharmGKB ID
KEGG ID rno:100911796 rno:25370
DIP ID DIP-217N
STRING ID 10116.ENSRNOP00000046340
IntAct ID
DMDM
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 100363178;25370;100911796
BindingDB P28647

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.830 0.005 0.988 0.000 0.909 0.003 0.901 0.003 0.968 0.004 0.830 0.005 Download
Estate fingerprints 0.802 0.008 0.918 0.004 0.860 0.005 0.852 0.008 0.942 0.004 0.727 0.011 Download
MACCS fingerprints 0.765 0.007 0.967 0.005 0.866 0.005 0.854 0.005 0.940 0.000 0.746 0.008 Download
Daylight fingerprints 0.831 0.007 0.977 0.007 0.904 0.005 0.897 0.005 0.950 0.000 0.819 0.007 Download
ECFP2 fingerprints 0.888 0.004 0.972 0.000 0.930 0.000 0.928 0.004 0.980 0.000 0.860 0.000 Download
ECFP4 fingerprints 0.881 0.009 0.973 0.000 0.927 0.005 0.924 0.005 0.980 0.000 0.857 0.005 Download
ECFP6 fingerprints 0.870 0.000 0.990 0.000 0.930 0.000 0.930 0.000 0.980 0.000 0.870 0.000 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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