Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
| Uniprot primary ID | P29274 |
| PDB ID | 4UG2 3EML 3QAK 1UPE 3PWH 1MMH 3VGA 4UHR 2YDO 3REY 3VG9 2YDV 4EIY 3RFM 3UZC 3UZA |
| DrugBank ID | DB00651 DB00640 DB06213 DB01412 DB00201 DB00824 DB00806 |
| BioGrid ID | 106647 |
| GuidetoPHARMACOLOGY ID | 19 |
| PharmGKB ID | PA24584 |
| KEGG ID | hsa:135 |
| DIP ID | |
| STRING ID | 9606.ENSP00000336630 |
| IntAct ID | P29274 |
| DMDM | 543740 |
| BRENDA | |
| Reactome | R-HSA-187024 R-HSA-418555 R-HSA-417973 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 135 |
| BindingDB | P29274 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.877 | 0.005 | 0.903 | 0.005 | 0.890 | 0.000 | 0.890 | 0.000 | 0.950 | 0.000 | 0.780 | 0.000 | Download |
| Estate fingerprints | 0.838 | 0.004 | 0.762 | 0.000 | 0.800 | 0.000 | 0.810 | 0.000 | 0.890 | 0.000 | 0.609 | 0.003 | Download |
| MACCS fingerprints | 0.901 | 0.003 | 0.799 | 0.000 | 0.850 | 0.000 | 0.860 | 0.000 | 0.930 | 0.000 | 0.709 | 0.003 | Download |
| Daylight fingerprints | 0.780 | 0.000 | 0.820 | 0.000 | 0.800 | 0.000 | 0.800 | 0.000 | 0.850 | 0.000 | 0.610 | 0.000 | Download |
| ECFP2 fingerprints | 0.940 | 0.000 | 0.900 | 0.005 | 0.920 | 0.000 | 0.923 | 0.005 | 0.980 | 0.000 | 0.849 | 0.003 | Download |
| ECFP4 fingerprints | 0.904 | 0.005 | 0.976 | 0.000 | 0.940 | 0.000 | 0.939 | 0.003 | 0.980 | 0.000 | 0.879 | 0.003 | Download |
| ECFP6 fingerprints | 0.866 | 0.005 | 0.974 | 0.000 | 0.920 | 0.000 | 0.920 | 0.000 | 0.980 | 0.000 | 0.850 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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