Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Uniprot primary ID | P29274 |
PDB ID | 4UG2 3EML 3QAK 1UPE 3PWH 1MMH 3VGA 4UHR 2YDO 3REY 3VG9 2YDV 4EIY 3RFM 3UZC 3UZA |
DrugBank ID | DB00651 DB00640 DB06213 DB01412 DB00201 DB00824 DB00806 |
BioGrid ID | 106647 |
GuidetoPHARMACOLOGY ID | 19 |
PharmGKB ID | PA24584 |
KEGG ID | hsa:135 |
DIP ID | |
STRING ID | 9606.ENSP00000336630 |
IntAct ID | P29274 |
DMDM | 543740 |
BRENDA | |
Reactome | R-HSA-187024 R-HSA-418555 R-HSA-417973 |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 135 |
BindingDB | P29274 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.877 | 0.005 | 0.903 | 0.005 | 0.890 | 0.000 | 0.890 | 0.000 | 0.950 | 0.000 | 0.780 | 0.000 | Download |
Estate fingerprints | 0.838 | 0.004 | 0.762 | 0.000 | 0.800 | 0.000 | 0.810 | 0.000 | 0.890 | 0.000 | 0.609 | 0.003 | Download |
MACCS fingerprints | 0.901 | 0.003 | 0.799 | 0.000 | 0.850 | 0.000 | 0.860 | 0.000 | 0.930 | 0.000 | 0.709 | 0.003 | Download |
Daylight fingerprints | 0.780 | 0.000 | 0.820 | 0.000 | 0.800 | 0.000 | 0.800 | 0.000 | 0.850 | 0.000 | 0.610 | 0.000 | Download |
ECFP2 fingerprints | 0.940 | 0.000 | 0.900 | 0.005 | 0.920 | 0.000 | 0.923 | 0.005 | 0.980 | 0.000 | 0.849 | 0.003 | Download |
ECFP4 fingerprints | 0.904 | 0.005 | 0.976 | 0.000 | 0.940 | 0.000 | 0.939 | 0.003 | 0.980 | 0.000 | 0.879 | 0.003 | Download |
ECFP6 fingerprints | 0.866 | 0.005 | 0.974 | 0.000 | 0.920 | 0.000 | 0.920 | 0.000 | 0.980 | 0.000 | 0.850 | 0.000 | Download |
Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn