Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
| Uniprot primary ID | P29275 |
| PDB ID | |
| DrugBank ID | DB00640 DB00824 DB00277 DB04932 |
| BioGrid ID | 106648 |
| GuidetoPHARMACOLOGY ID | 20 |
| PharmGKB ID | PA24585 |
| KEGG ID | hsa:136 |
| DIP ID | |
| STRING ID | 9606.ENSP00000304501 |
| IntAct ID | P29275 |
| DMDM | 112938 |
| BRENDA | |
| Reactome | R-HSA-418555 R-HSA-417973 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 136 |
| BindingDB | P29275 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.877 | 0.005 | 0.943 | 0.000 | 0.910 | 0.000 | 0.910 | 0.000 | 0.961 | 0.003 | 0.820 | 0.000 | Download |
| Estate fingerprints | 0.860 | 0.000 | 0.800 | 0.000 | 0.830 | 0.000 | 0.835 | 0.005 | 0.910 | 0.000 | 0.661 | 0.003 | Download |
| MACCS fingerprints | 0.850 | 0.000 | 0.850 | 0.003 | 0.850 | 0.000 | 0.850 | 0.000 | 0.940 | 0.000 | 0.705 | 0.005 | Download |
| Daylight fingerprints | 0.809 | 0.003 | 0.891 | 0.000 | 0.850 | 0.000 | 0.840 | 0.000 | 0.910 | 0.000 | 0.700 | 0.000 | Download |
| ECFP2 fingerprints | 0.938 | 0.004 | 0.942 | 0.000 | 0.940 | 0.000 | 0.940 | 0.000 | 0.980 | 0.000 | 0.873 | 0.005 | Download |
| ECFP4 fingerprints | 0.910 | 0.000 | 0.986 | 0.000 | 0.948 | 0.004 | 0.942 | 0.004 | 0.990 | 0.000 | 0.892 | 0.004 | Download |
| ECFP6 fingerprints | 0.876 | 0.005 | 0.984 | 0.000 | 0.930 | 0.000 | 0.928 | 0.004 | 0.990 | 0.000 | 0.866 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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