Target name

P29275: Adenosine receptor A2b


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P29275
PDB ID
DrugBank ID DB00640 DB00824 DB00277 DB04932
BioGrid ID 106648
GuidetoPHARMACOLOGY ID 20
PharmGKB ID PA24585
KEGG ID hsa:136
DIP ID
STRING ID 9606.ENSP00000304501
IntAct ID P29275
DMDM 112938
BRENDA
Reactome R-HSA-418555 R-HSA-417973
SignaLink
BioCyc
Entrez Gene (Gene ID) 136
BindingDB P29275

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.877 0.005 0.943 0.000 0.910 0.000 0.910 0.000 0.961 0.003 0.820 0.000 Download
Estate fingerprints 0.860 0.000 0.800 0.000 0.830 0.000 0.835 0.005 0.910 0.000 0.661 0.003 Download
MACCS fingerprints 0.850 0.000 0.850 0.003 0.850 0.000 0.850 0.000 0.940 0.000 0.705 0.005 Download
Daylight fingerprints 0.809 0.003 0.891 0.000 0.850 0.000 0.840 0.000 0.910 0.000 0.700 0.000 Download
ECFP2 fingerprints 0.938 0.004 0.942 0.000 0.940 0.000 0.940 0.000 0.980 0.000 0.873 0.005 Download
ECFP4 fingerprints 0.910 0.000 0.986 0.000 0.948 0.004 0.942 0.004 0.990 0.000 0.892 0.004 Download
ECFP6 fingerprints 0.876 0.005 0.984 0.000 0.930 0.000 0.928 0.004 0.990 0.000 0.866 0.005 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn