Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
| Uniprot primary ID | P29475 |
| PDB ID | 4UH5 4D1N 4UH6 4UCH 4V3U |
| DrugBank ID | DB00997 DB03147 DB00155 |
| BioGrid ID | 110905 |
| GuidetoPHARMACOLOGY ID | 1251 |
| PharmGKB ID | PA252 |
| KEGG ID | hsa:4842 |
| DIP ID | DIP-40999N |
| STRING ID | 9606.ENSP00000337459 |
| IntAct ID | P29475 |
| DMDM | 1709333 |
| BRENDA | 1.14.13.39 |
| Reactome | R-HSA-1222556 R-HSA-392154 |
| SignaLink | |
| BioCyc | MetaCyc:HS01647-MONOMER |
| Entrez Gene (Gene ID) | 4842 |
| BindingDB | P29475 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.867 | 0.005 | 0.917 | 0.000 | 0.892 | 0.004 | 0.890 | 0.000 | 0.960 | 0.000 | 0.784 | 0.005 | Download |
| Estate fingerprints | 0.797 | 0.005 | 0.883 | 0.003 | 0.840 | 0.000 | 0.832 | 0.004 | 0.920 | 0.000 | 0.683 | 0.005 | Download |
| MACCS fingerprints | 0.810 | 0.005 | 0.876 | 0.000 | 0.843 | 0.005 | 0.840 | 0.000 | 0.940 | 0.000 | 0.692 | 0.004 | Download |
| Daylight fingerprints | 0.652 | 0.004 | 0.834 | 0.005 | 0.743 | 0.005 | 0.720 | 0.000 | 0.810 | 0.000 | 0.497 | 0.005 | Download |
| ECFP2 fingerprints | 0.960 | 0.000 | 0.942 | 0.003 | 0.951 | 0.003 | 0.951 | 0.003 | 0.990 | 0.000 | 0.905 | 0.005 | Download |
| ECFP4 fingerprints | 0.965 | 0.005 | 0.965 | 0.005 | 0.965 | 0.005 | 0.965 | 0.005 | 0.997 | 0.005 | 0.930 | 0.000 | Download |
| ECFP6 fingerprints | 0.953 | 0.005 | 0.977 | 0.003 | 0.965 | 0.005 | 0.965 | 0.005 | 0.990 | 0.000 | 0.932 | 0.004 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: jiedong@csu.edu.cn
 |
 |
 |
 |
 |
 |