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E-mail: biomed@csu.edu.cn
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Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.
| Uniprot primary ID | P29476 |
| PDB ID | 2G6K 2G6J 2G6I 2G6H 2G6N 2G6M 2G6L 4UH4 4CTU 4UH1 4UH0 4UH3 4UH2 4K5D 4K5E 4K5F 1F20 4CAQ 4CAM 4CAN 4CAO 4JSG 3JWU 1ZVI 4IMU 3B3N 3B3O 3B3M 3B3P 4GQE 1TLL 4HOP 4CX3 5AGK 3JWT 4V3X 5AGO 3JWS 5AGM 5AGL 4K5G 4UPM 4UPO 4UPN 3TYN 4JSE 4D2Y 4UPP 4C39 3JWV 3NNY |
| DrugBank ID | |
| BioGrid ID | 246738 |
| GuidetoPHARMACOLOGY ID | 1251 |
| PharmGKB ID | |
| KEGG ID | rno:24598 |
| DIP ID | DIP-33272N |
| STRING ID | 10116.ENSRNOP00000062735 |
| IntAct ID | P29476 |
| DMDM | |
| BRENDA | 1.14.13.39 |
| Reactome | |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 24598 |
| BindingDB | P29476 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.948 | 0.010 | 0.910 | 0.007 | 0.929 | 0.003 | 0.932 | 0.006 | 0.980 | 0.000 | 0.861 | 0.013 | Download |
| Estate fingerprints | 0.886 | 0.010 | 0.912 | 0.007 | 0.899 | 0.006 | 0.898 | 0.004 | 0.950 | 0.000 | 0.798 | 0.008 | Download |
| MACCS fingerprints | 0.879 | 0.007 | 0.917 | 0.005 | 0.898 | 0.006 | 0.897 | 0.005 | 0.960 | 0.000 | 0.800 | 0.008 | Download |
| Daylight fingerprints | 0.761 | 0.003 | 0.841 | 0.003 | 0.801 | 0.003 | 0.793 | 0.005 | 0.870 | 0.000 | 0.608 | 0.006 | Download |
| ECFP2 fingerprints | 0.917 | 0.007 | 0.945 | 0.003 | 0.931 | 0.003 | 0.931 | 0.003 | 0.980 | 0.000 | 0.866 | 0.005 | Download |
| ECFP4 fingerprints | 0.936 | 0.005 | 0.964 | 0.005 | 0.950 | 0.000 | 0.949 | 0.003 | 0.990 | 0.000 | 0.902 | 0.006 | Download |
| ECFP6 fingerprints | 0.941 | 0.007 | 0.967 | 0.005 | 0.954 | 0.005 | 0.954 | 0.005 | 0.990 | 0.000 | 0.911 | 0.010 | Download |
| Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn
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