Target name

P30411: B2 bradykinin receptor


  Protein function

Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P30411
PDB ID
DrugBank ID DB06196
BioGrid ID 107093
GuidetoPHARMACOLOGY ID 42
PharmGKB ID PA80
KEGG ID hsa:624
DIP ID
STRING ID 9606.ENSP00000307713
IntAct ID P30411
DMDM 2506481
BRENDA
Reactome R-HSA-418594 R-HSA-375276 R-HSA-416476
SignaLink
BioCyc
Entrez Gene (Gene ID) 624
BindingDB P30411

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.810 0.000 0.990 0.000 0.900 0.000 0.890 0.000 0.950 0.000 0.820 0.000 Download
Estate fingerprints 0.800 0.000 0.880 0.004 0.840 0.000 0.831 0.003 0.880 0.000 0.683 0.005 Download
MACCS fingerprints 0.780 0.005 0.900 0.004 0.840 0.000 0.829 0.003 0.920 0.000 0.678 0.004 Download
Daylight fingerprints 0.828 0.004 0.960 0.004 0.894 0.005 0.888 0.004 0.930 0.000 0.795 0.005 Download
ECFP2 fingerprints 0.859 0.007 1.000 0.000 0.930 0.005 0.924 0.005 0.980 0.000 0.868 0.006 Download
ECFP4 fingerprints 0.870 0.000 0.996 0.000 0.933 0.005 0.930 0.000 0.990 0.000 0.880 0.000 Download
ECFP6 fingerprints 0.859 0.003 1.000 0.000 0.930 0.000 0.924 0.005 0.990 0.000 0.869 0.003 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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