Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
Uniprot primary ID | P30542 |
PDB ID | |
DrugBank ID | DB00996 DB00651 DB00640 DB01223 DB01412 DB00201 DB00824 |
BioGrid ID | 106646 |
GuidetoPHARMACOLOGY ID | 18 |
PharmGKB ID | PA24583 |
KEGG ID | hsa:134 |
DIP ID | |
STRING ID | 9606.ENSP00000308549 |
IntAct ID | P30542 |
DMDM | 231473 |
BRENDA | |
Reactome | R-HSA-418594 R-HSA-417973 |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 134 |
BindingDB | P30542 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.860 | 0.000 | 0.920 | 0.000 | 0.890 | 0.000 | 0.880 | 0.000 | 0.950 | 0.000 | 0.771 | 0.003 | Download |
Estate fingerprints | 0.830 | 0.000 | 0.750 | 0.000 | 0.790 | 0.000 | 0.800 | 0.000 | 0.880 | 0.000 | 0.590 | 0.000 | Download |
MACCS fingerprints | 0.890 | 0.000 | 0.790 | 0.000 | 0.840 | 0.000 | 0.850 | 0.000 | 0.930 | 0.000 | 0.681 | 0.003 | Download |
Daylight fingerprints | 0.760 | 0.000 | 0.840 | 0.000 | 0.800 | 0.000 | 0.790 | 0.000 | 0.860 | 0.000 | 0.598 | 0.004 | Download |
ECFP2 fingerprints | 0.930 | 0.000 | 0.910 | 0.000 | 0.920 | 0.000 | 0.920 | 0.000 | 0.970 | 0.000 | 0.840 | 0.000 | Download |
ECFP4 fingerprints | 0.905 | 0.005 | 0.975 | 0.003 | 0.940 | 0.000 | 0.930 | 0.000 | 0.980 | 0.000 | 0.870 | 0.000 | Download |
ECFP6 fingerprints | 0.862 | 0.004 | 0.978 | 0.000 | 0.920 | 0.000 | 0.914 | 0.005 | 0.980 | 0.000 | 0.843 | 0.005 | Download |
Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn