Target name

P30542: Adenosine receptor A1


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

  Database links

Uniprot primary ID P30542
PDB ID
DrugBank ID DB00996 DB00651 DB00640 DB01223 DB01412 DB00201 DB00824
BioGrid ID 106646
GuidetoPHARMACOLOGY ID 18
PharmGKB ID PA24583
KEGG ID hsa:134
DIP ID
STRING ID 9606.ENSP00000308549
IntAct ID P30542
DMDM 231473
BRENDA
Reactome R-HSA-418594 R-HSA-417973
SignaLink
BioCyc
Entrez Gene (Gene ID) 134
BindingDB P30542

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.860 0.000 0.920 0.000 0.890 0.000 0.880 0.000 0.950 0.000 0.771 0.003 Download
Estate fingerprints 0.830 0.000 0.750 0.000 0.790 0.000 0.800 0.000 0.880 0.000 0.590 0.000 Download
MACCS fingerprints 0.890 0.000 0.790 0.000 0.840 0.000 0.850 0.000 0.930 0.000 0.681 0.003 Download
Daylight fingerprints 0.760 0.000 0.840 0.000 0.800 0.000 0.790 0.000 0.860 0.000 0.598 0.004 Download
ECFP2 fingerprints 0.930 0.000 0.910 0.000 0.920 0.000 0.920 0.000 0.970 0.000 0.840 0.000 Download
ECFP4 fingerprints 0.905 0.005 0.975 0.003 0.940 0.000 0.930 0.000 0.980 0.000 0.870 0.000 Download
ECFP6 fingerprints 0.862 0.004 0.978 0.000 0.920 0.000 0.914 0.005 0.980 0.000 0.843 0.005 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn