Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
| Uniprot primary ID | P30542 |
| PDB ID | |
| DrugBank ID | DB00996 DB00651 DB00640 DB01223 DB01412 DB00201 DB00824 |
| BioGrid ID | 106646 |
| GuidetoPHARMACOLOGY ID | 18 |
| PharmGKB ID | PA24583 |
| KEGG ID | hsa:134 |
| DIP ID | |
| STRING ID | 9606.ENSP00000308549 |
| IntAct ID | P30542 |
| DMDM | 231473 |
| BRENDA | |
| Reactome | R-HSA-418594 R-HSA-417973 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 134 |
| BindingDB | P30542 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.860 | 0.000 | 0.920 | 0.000 | 0.890 | 0.000 | 0.880 | 0.000 | 0.950 | 0.000 | 0.771 | 0.003 | Download |
| Estate fingerprints | 0.830 | 0.000 | 0.750 | 0.000 | 0.790 | 0.000 | 0.800 | 0.000 | 0.880 | 0.000 | 0.590 | 0.000 | Download |
| MACCS fingerprints | 0.890 | 0.000 | 0.790 | 0.000 | 0.840 | 0.000 | 0.850 | 0.000 | 0.930 | 0.000 | 0.681 | 0.003 | Download |
| Daylight fingerprints | 0.760 | 0.000 | 0.840 | 0.000 | 0.800 | 0.000 | 0.790 | 0.000 | 0.860 | 0.000 | 0.598 | 0.004 | Download |
| ECFP2 fingerprints | 0.930 | 0.000 | 0.910 | 0.000 | 0.920 | 0.000 | 0.920 | 0.000 | 0.970 | 0.000 | 0.840 | 0.000 | Download |
| ECFP4 fingerprints | 0.905 | 0.005 | 0.975 | 0.003 | 0.940 | 0.000 | 0.930 | 0.000 | 0.980 | 0.000 | 0.870 | 0.000 | Download |
| ECFP6 fingerprints | 0.862 | 0.004 | 0.978 | 0.000 | 0.920 | 0.000 | 0.914 | 0.005 | 0.980 | 0.000 | 0.843 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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