Target name

P30543: Adenosine receptor A2a


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P30543
PDB ID
DrugBank ID
BioGrid ID 247408
GuidetoPHARMACOLOGY ID 19
PharmGKB ID
KEGG ID rno:25369
DIP ID
STRING ID 10116.ENSRNOP00000001759
IntAct ID P30543
DMDM
BRENDA
Reactome R-RNO-417973 R-RNO-418555 R-RNO-187024
SignaLink
BioCyc
Entrez Gene (Gene ID) 25369
BindingDB P30543

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.880 0.000 0.960 0.005 0.920 0.000 0.912 0.004 0.960 0.000 0.840 0.000 Download
Estate fingerprints 0.880 0.000 0.820 0.003 0.850 0.000 0.860 0.000 0.920 0.000 0.708 0.004 Download
MACCS fingerprints 0.860 0.000 0.840 0.004 0.850 0.000 0.854 0.005 0.930 0.000 0.708 0.004 Download
Daylight fingerprints 0.874 0.005 0.906 0.000 0.890 0.000 0.889 0.003 0.920 0.000 0.775 0.005 Download
ECFP2 fingerprints 0.920 0.000 0.940 0.000 0.930 0.000 0.930 0.000 0.980 0.000 0.860 0.000 Download
ECFP4 fingerprints 0.890 0.000 0.970 0.005 0.930 0.000 0.930 0.000 0.980 0.000 0.870 0.000 Download
ECFP6 fingerprints 0.871 0.003 0.987 0.000 0.929 0.003 0.920 0.000 0.980 0.000 0.860 0.000 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn