Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Uniprot primary ID | P30556 |
PDB ID | 1ZV0 4YAY |
DrugBank ID | DB01029 DB00876 DB01349 DB00678 DB08822 DB01347 DB00796 |
BioGrid ID | 106691 |
GuidetoPHARMACOLOGY ID | 34 |
PharmGKB ID | PA43 |
KEGG ID | hsa:185 |
DIP ID | |
STRING ID | 9606.ENSP00000273430 |
IntAct ID | P30556 |
DMDM | 231519 |
BRENDA | |
Reactome | R-HSA-375276 R-HSA-416476 |
SignaLink | P30556 |
BioCyc | |
Entrez Gene (Gene ID) | 185 |
BindingDB | P30556 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.840 | 0.000 | 0.980 | 0.000 | 0.910 | 0.000 | 0.900 | 0.000 | 0.940 | 0.000 | 0.820 | 0.000 | Download |
Estate fingerprints | 0.870 | 0.000 | 0.790 | 0.004 | 0.830 | 0.000 | 0.840 | 0.000 | 0.910 | 0.000 | 0.667 | 0.005 | Download |
MACCS fingerprints | 0.845 | 0.005 | 0.895 | 0.003 | 0.870 | 0.000 | 0.867 | 0.005 | 0.920 | 0.000 | 0.740 | 0.000 | Download |
Daylight fingerprints | 0.837 | 0.005 | 0.863 | 0.000 | 0.850 | 0.000 | 0.849 | 0.003 | 0.860 | 0.000 | 0.696 | 0.005 | Download |
ECFP2 fingerprints | 0.890 | 0.000 | 0.970 | 0.005 | 0.930 | 0.000 | 0.930 | 0.000 | 0.970 | 0.000 | 0.869 | 0.003 | Download |
ECFP4 fingerprints | 0.890 | 0.000 | 0.990 | 0.000 | 0.940 | 0.000 | 0.940 | 0.000 | 0.970 | 0.000 | 0.890 | 0.000 | Download |
ECFP6 fingerprints | 0.880 | 0.000 | 1.000 | 0.000 | 0.940 | 0.000 | 0.930 | 0.000 | 0.970 | 0.000 | 0.880 | 0.000 | Download |
Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn