Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
| Uniprot primary ID | P30556 |
| PDB ID | 1ZV0 4YAY |
| DrugBank ID | DB01029 DB00876 DB01349 DB00678 DB08822 DB01347 DB00796 |
| BioGrid ID | 106691 |
| GuidetoPHARMACOLOGY ID | 34 |
| PharmGKB ID | PA43 |
| KEGG ID | hsa:185 |
| DIP ID | |
| STRING ID | 9606.ENSP00000273430 |
| IntAct ID | P30556 |
| DMDM | 231519 |
| BRENDA | |
| Reactome | R-HSA-375276 R-HSA-416476 |
| SignaLink | P30556 |
| BioCyc | |
| Entrez Gene (Gene ID) | 185 |
| BindingDB | P30556 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.840 | 0.000 | 0.980 | 0.000 | 0.910 | 0.000 | 0.900 | 0.000 | 0.940 | 0.000 | 0.820 | 0.000 | Download |
| Estate fingerprints | 0.870 | 0.000 | 0.790 | 0.004 | 0.830 | 0.000 | 0.840 | 0.000 | 0.910 | 0.000 | 0.667 | 0.005 | Download |
| MACCS fingerprints | 0.845 | 0.005 | 0.895 | 0.003 | 0.870 | 0.000 | 0.867 | 0.005 | 0.920 | 0.000 | 0.740 | 0.000 | Download |
| Daylight fingerprints | 0.837 | 0.005 | 0.863 | 0.000 | 0.850 | 0.000 | 0.849 | 0.003 | 0.860 | 0.000 | 0.696 | 0.005 | Download |
| ECFP2 fingerprints | 0.890 | 0.000 | 0.970 | 0.005 | 0.930 | 0.000 | 0.930 | 0.000 | 0.970 | 0.000 | 0.869 | 0.003 | Download |
| ECFP4 fingerprints | 0.890 | 0.000 | 0.990 | 0.000 | 0.940 | 0.000 | 0.940 | 0.000 | 0.970 | 0.000 | 0.890 | 0.000 | Download |
| ECFP6 fingerprints | 0.880 | 0.000 | 1.000 | 0.000 | 0.940 | 0.000 | 0.930 | 0.000 | 0.970 | 0.000 | 0.880 | 0.000 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: jiedong@csu.edu.cn
 |
 |
 |
 |
 |
 |