Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
| Uniprot primary ID | P30559 |
| PDB ID | |
| DrugBank ID | DB01282 DB00107 |
| BioGrid ID | 111061 |
| GuidetoPHARMACOLOGY ID | 369 |
| PharmGKB ID | PA32858 |
| KEGG ID | hsa:5021 |
| DIP ID | |
| STRING ID | 9606.ENSP00000324270 |
| IntAct ID | |
| DMDM | 143811431 |
| BRENDA | |
| Reactome | R-HSA-388479 R-HSA-416476 |
| SignaLink | P30559 |
| BioCyc | |
| Entrez Gene (Gene ID) | 5021 |
| BindingDB | P30559 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.835 | 0.005 | 0.933 | 0.003 | 0.884 | 0.005 | 0.876 | 0.005 | 0.956 | 0.005 | 0.770 | 0.008 | Download |
| Estate fingerprints | 0.847 | 0.005 | 0.735 | 0.003 | 0.791 | 0.003 | 0.800 | 0.000 | 0.860 | 0.000 | 0.588 | 0.004 | Download |
| MACCS fingerprints | 0.845 | 0.005 | 0.751 | 0.006 | 0.798 | 0.004 | 0.806 | 0.005 | 0.876 | 0.005 | 0.595 | 0.007 | Download |
| Daylight fingerprints | 0.835 | 0.005 | 0.809 | 0.000 | 0.822 | 0.004 | 0.827 | 0.005 | 0.861 | 0.003 | 0.647 | 0.005 | Download |
| ECFP2 fingerprints | 0.939 | 0.003 | 0.961 | 0.004 | 0.950 | 0.000 | 0.950 | 0.000 | 0.980 | 0.000 | 0.903 | 0.005 | Download |
| ECFP4 fingerprints | 0.931 | 0.003 | 0.983 | 0.000 | 0.957 | 0.005 | 0.954 | 0.005 | 0.987 | 0.005 | 0.914 | 0.005 | Download |
| ECFP6 fingerprints | 0.907 | 0.007 | 0.985 | 0.000 | 0.946 | 0.005 | 0.944 | 0.005 | 0.981 | 0.003 | 0.897 | 0.007 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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