Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Involved in social memory formation.
| Uniprot primary ID | P30560 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 366 |
| PharmGKB ID | |
| KEGG ID | rno:25107 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000005829 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-388479 R-RNO-416476 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 25107 |
| BindingDB | P30560 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.910 | 0.007 | 0.888 | 0.004 | 0.899 | 0.003 | 0.901 | 0.003 | 0.960 | 0.000 | 0.800 | 0.008 | Download |
| Estate fingerprints | 0.924 | 0.005 | 0.780 | 0.005 | 0.852 | 0.004 | 0.862 | 0.004 | 0.910 | 0.000 | 0.713 | 0.007 | Download |
| MACCS fingerprints | 0.903 | 0.007 | 0.811 | 0.003 | 0.857 | 0.005 | 0.860 | 0.005 | 0.943 | 0.005 | 0.715 | 0.010 | Download |
| Daylight fingerprints | 0.873 | 0.005 | 0.951 | 0.000 | 0.912 | 0.004 | 0.909 | 0.003 | 0.950 | 0.000 | 0.828 | 0.004 | Download |
| ECFP2 fingerprints | 0.967 | 0.005 | 0.939 | 0.006 | 0.953 | 0.005 | 0.954 | 0.005 | 0.990 | 0.000 | 0.908 | 0.006 | Download |
| ECFP4 fingerprints | 0.967 | 0.005 | 0.967 | 0.005 | 0.967 | 0.005 | 0.967 | 0.005 | 0.990 | 0.000 | 0.935 | 0.005 | Download |
| ECFP6 fingerprints | 0.955 | 0.005 | 0.981 | 0.003 | 0.968 | 0.004 | 0.968 | 0.004 | 0.990 | 0.000 | 0.937 | 0.007 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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