Target name

P30560: Vasopressin V1a receptor


  Protein function

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Involved in social memory formation.

  Database links

Uniprot primary ID P30560
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 366
PharmGKB ID
KEGG ID rno:25107
DIP ID
STRING ID 10116.ENSRNOP00000005829
IntAct ID
DMDM
BRENDA
Reactome R-RNO-388479 R-RNO-416476
SignaLink
BioCyc
Entrez Gene (Gene ID) 25107
BindingDB P30560

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.910 0.007 0.888 0.004 0.899 0.003 0.901 0.003 0.960 0.000 0.800 0.008 Download
Estate fingerprints 0.924 0.005 0.780 0.005 0.852 0.004 0.862 0.004 0.910 0.000 0.713 0.007 Download
MACCS fingerprints 0.903 0.007 0.811 0.003 0.857 0.005 0.860 0.005 0.943 0.005 0.715 0.010 Download
Daylight fingerprints 0.873 0.005 0.951 0.000 0.912 0.004 0.909 0.003 0.950 0.000 0.828 0.004 Download
ECFP2 fingerprints 0.967 0.005 0.939 0.006 0.953 0.005 0.954 0.005 0.990 0.000 0.908 0.006 Download
ECFP4 fingerprints 0.967 0.005 0.967 0.005 0.967 0.005 0.967 0.005 0.990 0.000 0.935 0.005 Download
ECFP6 fingerprints 0.955 0.005 0.981 0.003 0.968 0.004 0.968 0.004 0.990 0.000 0.937 0.007 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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