Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
| Uniprot primary ID | P30969 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 249567 |
| GuidetoPHARMACOLOGY ID | 256 |
| PharmGKB ID | |
| KEGG ID | rno:81668 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000002755 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 81668 |
| BindingDB | P30969 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.878 | 0.004 | 0.942 | 0.004 | 0.910 | 0.000 | 0.910 | 0.000 | 0.970 | 0.000 | 0.827 | 0.005 | Download |
| Estate fingerprints | 0.843 | 0.005 | 0.797 | 0.004 | 0.820 | 0.000 | 0.823 | 0.005 | 0.900 | 0.000 | 0.643 | 0.005 | Download |
| MACCS fingerprints | 0.883 | 0.005 | 0.837 | 0.003 | 0.860 | 0.000 | 0.865 | 0.005 | 0.940 | 0.000 | 0.725 | 0.005 | Download |
| Daylight fingerprints | 0.822 | 0.004 | 0.874 | 0.000 | 0.848 | 0.004 | 0.841 | 0.003 | 0.920 | 0.000 | 0.691 | 0.006 | Download |
| ECFP2 fingerprints | 0.896 | 0.005 | 0.960 | 0.003 | 0.928 | 0.004 | 0.926 | 0.005 | 0.980 | 0.000 | 0.857 | 0.005 | Download |
| ECFP4 fingerprints | 0.937 | 0.005 | 0.983 | 0.004 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.920 | 0.000 | Download |
| ECFP6 fingerprints | 0.931 | 0.003 | 0.989 | 0.000 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.921 | 0.003 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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