Target name

P31639: Sodium/glucose cotransporter 2


  Protein function

Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1.

  Database links

Uniprot primary ID P31639
PDB ID
DrugBank ID DB06292 DB09038 DB08907
BioGrid ID 112415
GuidetoPHARMACOLOGY ID 916
PharmGKB ID PA35902
KEGG ID hsa:6524
DIP ID
STRING ID 9606.ENSP00000327943
IntAct ID
DMDM 400337
BRENDA
Reactome R-HSA-189200 R-HSA-428808 R-HSA-429593
SignaLink
BioCyc
Entrez Gene (Gene ID) 6524
BindingDB P31639

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.904 0.005 0.982 0.000 0.943 0.005 0.940 0.000 0.990 0.000 0.893 0.005 Download
Estate fingerprints 0.860 0.000 0.934 0.000 0.897 0.005 0.890 0.000 0.960 0.000 0.792 0.004 Download
MACCS fingerprints 0.890 0.000 0.970 0.000 0.930 0.000 0.926 0.005 0.980 0.000 0.859 0.003 Download
Daylight fingerprints 0.903 0.005 0.977 0.000 0.940 0.000 0.940 0.000 0.990 0.000 0.890 0.000 Download
ECFP2 fingerprints 0.950 0.000 0.990 0.000 0.970 0.000 0.970 0.000 1.000 0.000 0.944 0.005 Download
ECFP4 fingerprints 0.976 0.005 1.000 0.000 0.990 0.000 0.990 0.000 1.000 0.000 0.970 0.000 Download
ECFP6 fingerprints 0.949 0.003 0.993 0.003 0.971 0.003 0.971 0.003 1.000 0.000 0.949 0.003 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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