Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
| Uniprot primary ID | P31648 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 929 |
| PharmGKB ID | |
| KEGG ID | mmu:232333 |
| DIP ID | |
| STRING ID | 10090.ENSMUSP00000032454 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-MMU-442660 R-MMU-888593 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 232333 |
| BindingDB | P31648 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.990 | 0.000 | 0.970 | 0.005 | 0.980 | 0.000 | 0.983 | 0.005 | 0.990 | 0.000 | 0.963 | 0.005 | Download |
| Estate fingerprints | 0.960 | 0.000 | 0.938 | 0.010 | 0.949 | 0.006 | 0.955 | 0.005 | 0.991 | 0.003 | 0.904 | 0.010 | Download |
| MACCS fingerprints | 0.970 | 0.000 | 0.982 | 0.007 | 0.976 | 0.005 | 0.976 | 0.005 | 0.993 | 0.005 | 0.957 | 0.007 | Download |
| Daylight fingerprints | 0.986 | 0.005 | 0.914 | 0.000 | 0.950 | 0.000 | 0.956 | 0.005 | 0.951 | 0.003 | 0.906 | 0.005 | Download |
| ECFP2 fingerprints | 0.963 | 0.005 | 0.983 | 0.000 | 0.973 | 0.005 | 0.973 | 0.005 | 1.000 | 0.000 | 0.953 | 0.005 | Download |
| ECFP4 fingerprints | 0.962 | 0.004 | 0.998 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 1.000 | 0.000 | 0.962 | 0.004 | Download |
| ECFP6 fingerprints | 0.957 | 0.005 | 0.997 | 0.000 | 0.977 | 0.005 | 0.977 | 0.005 | 1.000 | 0.000 | 0.957 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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