Target name

P31648: Sodium- and chloride-dependent GABA transporter 1


  Protein function

Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.

  Database links

Uniprot primary ID P31648
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 929
PharmGKB ID
KEGG ID mmu:232333
DIP ID
STRING ID 10090.ENSMUSP00000032454
IntAct ID
DMDM
BRENDA
Reactome R-MMU-442660 R-MMU-888593
SignaLink
BioCyc
Entrez Gene (Gene ID) 232333
BindingDB P31648

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.990 0.000 0.970 0.005 0.980 0.000 0.983 0.005 0.990 0.000 0.963 0.005 Download
Estate fingerprints 0.960 0.000 0.938 0.010 0.949 0.006 0.955 0.005 0.991 0.003 0.904 0.010 Download
MACCS fingerprints 0.970 0.000 0.982 0.007 0.976 0.005 0.976 0.005 0.993 0.005 0.957 0.007 Download
Daylight fingerprints 0.986 0.005 0.914 0.000 0.950 0.000 0.956 0.005 0.951 0.003 0.906 0.005 Download
ECFP2 fingerprints 0.963 0.005 0.983 0.000 0.973 0.005 0.973 0.005 1.000 0.000 0.953 0.005 Download
ECFP4 fingerprints 0.962 0.004 0.998 0.000 0.980 0.000 0.980 0.000 1.000 0.000 0.962 0.004 Download
ECFP6 fingerprints 0.957 0.005 0.997 0.000 0.977 0.005 0.977 0.005 1.000 0.000 0.957 0.005 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn