Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
| Uniprot primary ID | P32247 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 40 |
| PharmGKB ID | PA25427 |
| KEGG ID | hsa:680 |
| DIP ID | |
| STRING ID | 9606.ENSP00000359682 |
| IntAct ID | |
| DMDM | 416726 |
| BRENDA | |
| Reactome | R-HSA-375276 R-HSA-416476 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 680 |
| BindingDB | P32247 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.947 | 0.005 | 0.951 | 0.004 | 0.949 | 0.003 | 0.949 | 0.003 | 0.984 | 0.005 | 0.896 | 0.005 | Download |
| Estate fingerprints | 0.880 | 0.009 | 0.858 | 0.008 | 0.869 | 0.006 | 0.871 | 0.007 | 0.940 | 0.000 | 0.738 | 0.010 | Download |
| MACCS fingerprints | 0.891 | 0.013 | 0.905 | 0.009 | 0.898 | 0.011 | 0.898 | 0.011 | 0.960 | 0.000 | 0.798 | 0.020 | Download |
| Daylight fingerprints | 0.765 | 0.007 | 0.969 | 0.005 | 0.867 | 0.005 | 0.851 | 0.006 | 0.943 | 0.005 | 0.748 | 0.006 | Download |
| ECFP2 fingerprints | 0.930 | 0.007 | 0.928 | 0.005 | 0.929 | 0.006 | 0.929 | 0.006 | 0.989 | 0.003 | 0.855 | 0.008 | Download |
| ECFP4 fingerprints | 0.954 | 0.005 | 0.986 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.992 | 0.004 | 0.944 | 0.005 | Download |
| ECFP6 fingerprints | 0.936 | 0.007 | 0.996 | 0.000 | 0.966 | 0.005 | 0.966 | 0.005 | 0.998 | 0.004 | 0.935 | 0.007 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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