Target name

P32247: Bombesin receptor subtype-3


  Protein function

Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P32247
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 40
PharmGKB ID PA25427
KEGG ID hsa:680
DIP ID
STRING ID 9606.ENSP00000359682
IntAct ID
DMDM 416726
BRENDA
Reactome R-HSA-375276 R-HSA-416476
SignaLink
BioCyc
Entrez Gene (Gene ID) 680
BindingDB P32247

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.947 0.005 0.951 0.004 0.949 0.003 0.949 0.003 0.984 0.005 0.896 0.005 Download
Estate fingerprints 0.880 0.009 0.858 0.008 0.869 0.006 0.871 0.007 0.940 0.000 0.738 0.010 Download
MACCS fingerprints 0.891 0.013 0.905 0.009 0.898 0.011 0.898 0.011 0.960 0.000 0.798 0.020 Download
Daylight fingerprints 0.765 0.007 0.969 0.005 0.867 0.005 0.851 0.006 0.943 0.005 0.748 0.006 Download
ECFP2 fingerprints 0.930 0.007 0.928 0.005 0.929 0.006 0.929 0.006 0.989 0.003 0.855 0.008 Download
ECFP4 fingerprints 0.954 0.005 0.986 0.000 0.970 0.000 0.970 0.000 0.992 0.004 0.944 0.005 Download
ECFP6 fingerprints 0.936 0.007 0.996 0.000 0.966 0.005 0.966 0.005 0.998 0.004 0.935 0.007 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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