Target name

P32745: Somatostatin receptor type 3


  Protein function

Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.

  Database links

Uniprot primary ID P32745
PDB ID
DrugBank ID DB06663
BioGrid ID 112631
GuidetoPHARMACOLOGY ID 357
PharmGKB ID PA36156
KEGG ID hsa:6753
DIP ID
STRING ID 9606.ENSP00000330138
IntAct ID P32745
DMDM 417815
BRENDA
Reactome R-HSA-418594 R-HSA-5620922 R-HSA-375276
SignaLink
BioCyc
Entrez Gene (Gene ID) 6753
BindingDB P32745

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.893 0.007 0.965 0.005 0.929 0.003 0.928 0.004 0.970 0.000 0.862 0.006 Download
Estate fingerprints 0.860 0.000 0.950 0.000 0.905 0.005 0.900 0.000 0.970 0.000 0.812 0.004 Download
MACCS fingerprints 0.830 0.005 0.950 0.004 0.890 0.000 0.884 0.005 0.960 0.000 0.789 0.003 Download
Daylight fingerprints 0.849 0.003 0.971 0.000 0.910 0.000 0.903 0.005 0.970 0.000 0.823 0.005 Download
ECFP2 fingerprints 0.830 0.000 0.970 0.000 0.900 0.000 0.890 0.000 0.990 0.000 0.810 0.000 Download
ECFP4 fingerprints 0.837 0.005 0.983 0.000 0.910 0.000 0.900 0.000 0.990 0.000 0.830 0.000 Download
ECFP6 fingerprints 0.792 0.004 0.988 0.000 0.890 0.000 0.880 0.000 0.990 0.000 0.799 0.003 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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