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E-mail: biomed@csu.edu.cn
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Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.
| Uniprot primary ID | P33032 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 110331 |
| GuidetoPHARMACOLOGY ID | 286 |
| PharmGKB ID | PA30677 |
| KEGG ID | hsa:4161 |
| DIP ID | DIP-48792N |
| STRING ID | 9606.ENSP00000318077 |
| IntAct ID | P33032 |
| DMDM | 729996 |
| BRENDA | |
| Reactome | R-HSA-418555 R-HSA-375276 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 4161 |
| BindingDB | P33032 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.947 | 0.005 | 0.913 | 0.000 | 0.930 | 0.000 | 0.931 | 0.003 | 0.970 | 0.000 | 0.858 | 0.006 | Download |
| Estate fingerprints | 0.917 | 0.005 | 0.861 | 0.005 | 0.889 | 0.003 | 0.891 | 0.003 | 0.950 | 0.000 | 0.780 | 0.005 | Download |
| MACCS fingerprints | 0.922 | 0.004 | 0.848 | 0.006 | 0.885 | 0.005 | 0.890 | 0.000 | 0.960 | 0.000 | 0.774 | 0.005 | Download |
| Daylight fingerprints | 0.846 | 0.005 | 0.936 | 0.000 | 0.891 | 0.003 | 0.889 | 0.003 | 0.940 | 0.000 | 0.790 | 0.005 | Download |
| ECFP2 fingerprints | 0.947 | 0.005 | 0.947 | 0.003 | 0.947 | 0.005 | 0.947 | 0.005 | 0.980 | 0.000 | 0.896 | 0.007 | Download |
| ECFP4 fingerprints | 0.926 | 0.005 | 0.964 | 0.003 | 0.945 | 0.005 | 0.943 | 0.005 | 0.990 | 0.000 | 0.890 | 0.000 | Download |
| ECFP6 fingerprints | 0.886 | 0.005 | 0.974 | 0.000 | 0.930 | 0.000 | 0.927 | 0.005 | 0.988 | 0.004 | 0.864 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn
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