Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation (By similarity).
| Uniprot primary ID | P35351 |
| PDB ID | 2G2A |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 35 |
| PharmGKB ID | |
| KEGG ID | rno:24182 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000064709 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-418594 R-RNO-375276 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 24182 |
| BindingDB | P35351 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.879 | 0.003 | 1.000 | 0.000 | 0.940 | 0.000 | 0.931 | 0.003 | 0.960 | 0.000 | 0.880 | 0.000 | Download |
| Estate fingerprints | 0.890 | 0.000 | 0.870 | 0.000 | 0.880 | 0.000 | 0.880 | 0.000 | 0.929 | 0.003 | 0.760 | 0.000 | Download |
| MACCS fingerprints | 0.740 | 0.000 | 0.928 | 0.004 | 0.834 | 0.005 | 0.820 | 0.000 | 0.940 | 0.000 | 0.680 | 0.000 | Download |
| Daylight fingerprints | 0.870 | 0.000 | 0.950 | 0.000 | 0.910 | 0.000 | 0.903 | 0.005 | 0.930 | 0.000 | 0.816 | 0.005 | Download |
| ECFP2 fingerprints | 0.908 | 0.004 | 0.992 | 0.005 | 0.950 | 0.000 | 0.950 | 0.000 | 0.990 | 0.000 | 0.909 | 0.003 | Download |
| ECFP4 fingerprints | 0.922 | 0.004 | 0.998 | 0.005 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.922 | 0.004 | Download |
| ECFP6 fingerprints | 0.903 | 0.005 | 0.997 | 0.000 | 0.950 | 0.000 | 0.950 | 0.000 | 0.990 | 0.000 | 0.906 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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