Target name

P35351: Type-2 angiotensin II receptor


  Protein function

Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation (By similarity).

  Database links

Uniprot primary ID P35351
PDB ID 2G2A
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 35
PharmGKB ID
KEGG ID rno:24182
DIP ID
STRING ID 10116.ENSRNOP00000064709
IntAct ID
DMDM
BRENDA
Reactome R-RNO-418594 R-RNO-375276
SignaLink
BioCyc
Entrez Gene (Gene ID) 24182
BindingDB P35351

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.879 0.003 1.000 0.000 0.940 0.000 0.931 0.003 0.960 0.000 0.880 0.000 Download
Estate fingerprints 0.890 0.000 0.870 0.000 0.880 0.000 0.880 0.000 0.929 0.003 0.760 0.000 Download
MACCS fingerprints 0.740 0.000 0.928 0.004 0.834 0.005 0.820 0.000 0.940 0.000 0.680 0.000 Download
Daylight fingerprints 0.870 0.000 0.950 0.000 0.910 0.000 0.903 0.005 0.930 0.000 0.816 0.005 Download
ECFP2 fingerprints 0.908 0.004 0.992 0.005 0.950 0.000 0.950 0.000 0.990 0.000 0.909 0.003 Download
ECFP4 fingerprints 0.922 0.004 0.998 0.005 0.960 0.000 0.960 0.000 0.990 0.000 0.922 0.004 Download
ECFP6 fingerprints 0.903 0.005 0.997 0.000 0.950 0.000 0.950 0.000 0.990 0.000 0.906 0.005 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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