Target name

P37136: Acetylcholinesterase


  Protein function

Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.

  Database links

Uniprot primary ID P37136
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID rno:83817
DIP ID
STRING ID
IntAct ID
DMDM
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 83817
BindingDB P37136

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.858 0.004 0.874 0.006 0.866 0.005 0.865 0.005 0.940 0.000 0.730 0.008 Download
Estate fingerprints 0.731 0.006 0.733 0.005 0.732 0.004 0.730 0.000 0.830 0.000 0.464 0.005 Download
MACCS fingerprints 0.879 0.003 0.761 0.000 0.820 0.005 0.829 0.003 0.881 0.003 0.645 0.007 Download
Daylight fingerprints 0.808 0.010 0.874 0.006 0.841 0.007 0.834 0.007 0.910 0.000 0.682 0.012 Download
ECFP2 fingerprints 0.957 0.005 0.903 0.003 0.930 0.000 0.930 0.000 0.980 0.000 0.861 0.003 Download
ECFP4 fingerprints 0.949 0.003 0.967 0.005 0.958 0.004 0.955 0.005 0.990 0.000 0.910 0.000 Download
ECFP6 fingerprints 0.927 0.005 0.987 0.005 0.957 0.005 0.952 0.004 0.990 0.000 0.911 0.006 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn