Target name

P41149: Melanocortin receptor 5


  Protein function

Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

  Database links

Uniprot primary ID P41149
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 286
PharmGKB ID
KEGG ID
DIP ID
STRING ID 10090.ENSMUSP00000130497
IntAct ID
DMDM
BRENDA
Reactome R-MMU-418555 R-MMU-375276
SignaLink
BioCyc
Entrez Gene (Gene ID)
BindingDB P41149

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.980 0.000 0.980 0.000 0.980 0.000 0.980 0.000 0.990 0.000 0.970 0.000 Download
Estate fingerprints 0.979 0.003 0.981 0.000 0.980 0.000 0.980 0.000 1.000 0.000 0.960 0.000 Download
MACCS fingerprints 0.980 0.000 0.980 0.000 0.980 0.000 0.980 0.000 1.000 0.000 0.965 0.005 Download
Daylight fingerprints 0.974 0.005 0.986 0.000 0.980 0.000 0.980 0.000 0.990 0.000 0.954 0.005 Download
ECFP2 fingerprints 0.980 0.000 0.980 0.000 0.980 0.000 0.980 0.000 0.999 0.003 0.960 0.000 Download
ECFP4 fingerprints 0.980 0.000 0.980 0.000 0.980 0.000 0.980 0.000 1.000 0.000 0.963 0.005 Download
ECFP6 fingerprints 0.980 0.000 0.996 0.004 0.988 0.004 0.988 0.004 1.000 0.000 0.978 0.004 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn