Target name

P43166: Carbonic anhydrase 7


  Protein function

Reversible hydration of carbon dioxide.

  Database links

Uniprot primary ID P43166
PDB ID 3ML5 3MDZ
DrugBank ID DB00703 DB00819 DB01144 DB00909
BioGrid ID
GuidetoPHARMACOLOGY ID 2749
PharmGKB ID PA25996
KEGG ID hsa:766
DIP ID
STRING ID 9606.ENSP00000345659
IntAct ID
DMDM 1168744
BRENDA 4.2.1.1
Reactome R-HSA-1475029
SignaLink
BioCyc
Entrez Gene (Gene ID) 766
BindingDB P43166

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.948 0.006 0.878 0.003 0.913 0.005 0.914 0.005 0.969 0.003 0.828 0.006 Download
Estate fingerprints 0.872 0.006 0.900 0.006 0.886 0.005 0.886 0.005 0.960 0.000 0.773 0.011 Download
MACCS fingerprints 0.897 0.005 0.877 0.000 0.887 0.005 0.889 0.006 0.950 0.000 0.778 0.006 Download
Daylight fingerprints 0.727 0.007 0.855 0.003 0.791 0.003 0.779 0.003 0.850 0.000 0.590 0.005 Download
ECFP2 fingerprints 0.990 0.000 0.918 0.000 0.954 0.005 0.959 0.003 0.990 0.000 0.912 0.004 Download
ECFP4 fingerprints 0.989 0.003 0.931 0.006 0.960 0.000 0.960 0.000 0.990 0.000 0.921 0.007 Download
ECFP6 fingerprints 0.967 0.005 0.953 0.005 0.960 0.000 0.960 0.000 0.990 0.000 0.919 0.006 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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