Target name

P46925: Plasmepsin-2


  Protein function

  Database links

Uniprot primary ID P46925
PDB ID 1LF4 1W6H 1W6I 4CKU 1LF3 1SME 1LF2 1XDH 1LEE 2BJU 2BL3 2R9B 1ME6 2IGX 2IGY 1PFZ 1J8J 3F9Q 1XE5 1XE6 1M43
DrugBank ID DB01218
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID
DIP ID
STRING ID 5833.PF14_0077
IntAct ID
DMDM
BRENDA 3.4.23.39
Reactome
SignaLink
BioCyc MetaCyc:MONOMER-15374
Entrez Gene (Gene ID)
BindingDB P46925

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.930 0.000 0.928 0.004 0.929 0.003 0.929 0.003 0.950 0.000 0.852 0.006 Download
Estate fingerprints 0.809 0.003 0.773 0.005 0.791 0.003 0.795 0.005 0.899 0.003 0.586 0.005 Download
MACCS fingerprints 0.849 0.003 0.891 0.000 0.870 0.000 0.867 0.005 0.940 0.000 0.742 0.004 Download
Daylight fingerprints 0.810 0.000 0.950 0.000 0.880 0.000 0.870 0.000 0.930 0.000 0.769 0.003 Download
ECFP2 fingerprints 0.928 0.004 0.950 0.005 0.939 0.003 0.939 0.003 0.980 0.000 0.883 0.007 Download
ECFP4 fingerprints 0.939 0.003 0.977 0.000 0.958 0.004 0.954 0.005 0.990 0.000 0.910 0.005 Download
ECFP6 fingerprints 0.930 0.000 0.990 0.000 0.960 0.000 0.959 0.003 0.985 0.005 0.919 0.003 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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