TargetNet
  Target name

P47900: P2Y purinoceptor 1

  Protein function

Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.

  Database links
Uniprot primary ID P47900
PDB ID 4XNV 1Y36 4XNW
DrugBank ID
BioGrid ID 111067
GuidetoPHARMACOLOGY ID 323
PharmGKB ID PA32868
KEGG ID hsa:5028
DIP ID
STRING ID 9606.ENSP00000304767
IntAct ID P47900
DMDM 1352692
BRENDA
Reactome R-HSA-417957 R-HSA-416476 R-HSA-418592
SignaLink
BioCyc
Entrez Gene (Gene ID) 5028
BindingDB P47900
  Model Performance Metrics
Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.846 0.008 0.982 0.003 0.914 0.007 0.906 0.005 0.971 0.003 0.833 0.008 Download
Estate fingerprints 0.817 0.005 0.869 0.008 0.843 0.007 0.841 0.009 0.914 0.005 0.691 0.012 Download
MACCS fingerprints 0.900 0.005 0.946 0.003 0.923 0.005 0.921 0.003 0.980 0.000 0.846 0.005 Download
Daylight fingerprints 0.822 0.008 0.956 0.006 0.889 0.006 0.881 0.006 0.952 0.004 0.784 0.010 Download
ECFP2 fingerprints 0.945 0.005 0.995 0.000 0.970 0.000 0.970 0.000 0.999 0.003 0.939 0.006 Download
ECFP4 fingerprints 0.967 0.005 0.993 0.000 0.980 0.000 0.980 0.000 0.990 0.000 0.962 0.004 Download
ECFP6 fingerprints 0.968 0.004 0.992 0.000 0.980 0.000 0.980 0.000 0.990 0.000 0.964 0.005 Download
  Download datasets
Positive dataset Negative dataset

The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn