Target name

P47901: Vasopressin V1b receptor


  Protein function

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

  Database links

Uniprot primary ID P47901
PDB ID
DrugBank ID DB02638 DB00067 DB00035
BioGrid ID 107034
GuidetoPHARMACOLOGY ID 367
PharmGKB ID PA25188
KEGG ID hsa:553
DIP ID
STRING ID 9606.ENSP00000356094
IntAct ID
DMDM 1351392
BRENDA
Reactome R-HSA-388479 R-HSA-416476
SignaLink
BioCyc
Entrez Gene (Gene ID) 553
BindingDB P47901

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.970 0.000 0.972 0.004 0.971 0.003 0.971 0.003 0.990 0.000 0.947 0.005 Download
Estate fingerprints 0.961 0.007 0.807 0.010 0.884 0.007 0.891 0.006 0.967 0.005 0.774 0.012 Download
MACCS fingerprints 0.996 0.005 0.878 0.005 0.937 0.005 0.939 0.003 0.960 0.000 0.877 0.005 Download
Daylight fingerprints 0.921 0.006 0.917 0.003 0.919 0.003 0.919 0.003 0.960 0.000 0.839 0.007 Download
ECFP2 fingerprints 0.955 0.005 0.965 0.000 0.960 0.000 0.960 0.000 0.990 0.000 0.920 0.005 Download
ECFP4 fingerprints 0.953 0.007 0.979 0.003 0.966 0.005 0.966 0.005 1.000 0.000 0.931 0.006 Download
ECFP6 fingerprints 0.917 0.007 1.000 0.000 0.959 0.003 0.958 0.004 0.990 0.000 0.919 0.003 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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