Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
Uniprot primary ID | P47936 |
PDB ID | |
DrugBank ID | |
BioGrid ID | |
GuidetoPHARMACOLOGY ID | 57 |
PharmGKB ID | |
KEGG ID | mmu:12802 |
DIP ID | |
STRING ID | 10090.ENSMUSP00000069957 |
IntAct ID | |
DMDM | |
BRENDA | |
Reactome | R-MMU-373076 R-MMU-418594 |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 12802 |
BindingDB | P47936 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.795 | 0.005 | 0.925 | 0.003 | 0.860 | 0.000 | 0.851 | 0.003 | 0.950 | 0.000 | 0.726 | 0.007 | Download |
Estate fingerprints | 0.681 | 0.006 | 0.739 | 0.005 | 0.710 | 0.000 | 0.701 | 0.003 | 0.824 | 0.005 | 0.419 | 0.009 | Download |
MACCS fingerprints | 0.603 | 0.005 | 0.813 | 0.007 | 0.708 | 0.004 | 0.676 | 0.005 | 0.833 | 0.005 | 0.425 | 0.005 | Download |
Daylight fingerprints | 0.585 | 0.005 | 0.987 | 0.004 | 0.786 | 0.005 | 0.731 | 0.003 | 0.933 | 0.007 | 0.620 | 0.007 | Download |
ECFP2 fingerprints | 0.928 | 0.008 | 0.932 | 0.005 | 0.930 | 0.005 | 0.930 | 0.005 | 0.980 | 0.000 | 0.862 | 0.010 | Download |
ECFP4 fingerprints | 0.948 | 0.004 | 0.964 | 0.005 | 0.956 | 0.005 | 0.956 | 0.005 | 0.990 | 0.000 | 0.907 | 0.005 | Download |
ECFP6 fingerprints | 0.921 | 0.009 | 0.975 | 0.003 | 0.948 | 0.004 | 0.945 | 0.005 | 0.990 | 0.000 | 0.896 | 0.007 | Download |
Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn