Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
| Uniprot primary ID | P47936 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 57 |
| PharmGKB ID | |
| KEGG ID | mmu:12802 |
| DIP ID | |
| STRING ID | 10090.ENSMUSP00000069957 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-MMU-373076 R-MMU-418594 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 12802 |
| BindingDB | P47936 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.795 | 0.005 | 0.925 | 0.003 | 0.860 | 0.000 | 0.851 | 0.003 | 0.950 | 0.000 | 0.726 | 0.007 | Download |
| Estate fingerprints | 0.681 | 0.006 | 0.739 | 0.005 | 0.710 | 0.000 | 0.701 | 0.003 | 0.824 | 0.005 | 0.419 | 0.009 | Download |
| MACCS fingerprints | 0.603 | 0.005 | 0.813 | 0.007 | 0.708 | 0.004 | 0.676 | 0.005 | 0.833 | 0.005 | 0.425 | 0.005 | Download |
| Daylight fingerprints | 0.585 | 0.005 | 0.987 | 0.004 | 0.786 | 0.005 | 0.731 | 0.003 | 0.933 | 0.007 | 0.620 | 0.007 | Download |
| ECFP2 fingerprints | 0.928 | 0.008 | 0.932 | 0.005 | 0.930 | 0.005 | 0.930 | 0.005 | 0.980 | 0.000 | 0.862 | 0.010 | Download |
| ECFP4 fingerprints | 0.948 | 0.004 | 0.964 | 0.005 | 0.956 | 0.005 | 0.956 | 0.005 | 0.990 | 0.000 | 0.907 | 0.005 | Download |
| ECFP6 fingerprints | 0.921 | 0.009 | 0.975 | 0.003 | 0.948 | 0.004 | 0.945 | 0.005 | 0.990 | 0.000 | 0.896 | 0.007 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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