Target name

P47936: Cannabinoid receptor 2


  Protein function

Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.

  Database links

Uniprot primary ID P47936
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 57
PharmGKB ID
KEGG ID mmu:12802
DIP ID
STRING ID 10090.ENSMUSP00000069957
IntAct ID
DMDM
BRENDA
Reactome R-MMU-373076 R-MMU-418594
SignaLink
BioCyc
Entrez Gene (Gene ID) 12802
BindingDB P47936

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.795 0.005 0.925 0.003 0.860 0.000 0.851 0.003 0.950 0.000 0.726 0.007 Download
Estate fingerprints 0.681 0.006 0.739 0.005 0.710 0.000 0.701 0.003 0.824 0.005 0.419 0.009 Download
MACCS fingerprints 0.603 0.005 0.813 0.007 0.708 0.004 0.676 0.005 0.833 0.005 0.425 0.005 Download
Daylight fingerprints 0.585 0.005 0.987 0.004 0.786 0.005 0.731 0.003 0.933 0.007 0.620 0.007 Download
ECFP2 fingerprints 0.928 0.008 0.932 0.005 0.930 0.005 0.930 0.005 0.980 0.000 0.862 0.010 Download
ECFP4 fingerprints 0.948 0.004 0.964 0.005 0.956 0.005 0.956 0.005 0.990 0.000 0.907 0.005 Download
ECFP6 fingerprints 0.921 0.009 0.975 0.003 0.948 0.004 0.945 0.005 0.990 0.000 0.896 0.007 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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