Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
Uniprot primary ID | P48145 |
PDB ID | |
DrugBank ID | |
BioGrid ID | 109092 |
GuidetoPHARMACOLOGY ID | 303 |
PharmGKB ID | PA28912 |
KEGG ID | hsa:2831 |
DIP ID | |
STRING ID | 9606.ENSP00000330284 |
IntAct ID | |
DMDM | 215274092 |
BRENDA | |
Reactome | R-HSA-418594 R-HSA-375276 |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 2831 |
BindingDB | P48145 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.730 | 0.000 | 0.990 | 0.000 | 0.860 | 0.000 | 0.840 | 0.000 | 0.919 | 0.003 | 0.760 | 0.000 | Download |
Estate fingerprints | 0.739 | 0.003 | 0.867 | 0.007 | 0.803 | 0.005 | 0.791 | 0.003 | 0.845 | 0.005 | 0.614 | 0.007 | Download |
MACCS fingerprints | 0.757 | 0.007 | 0.963 | 0.005 | 0.860 | 0.000 | 0.845 | 0.005 | 0.891 | 0.003 | 0.735 | 0.005 | Download |
Daylight fingerprints | 0.730 | 0.000 | 0.990 | 0.000 | 0.860 | 0.000 | 0.840 | 0.000 | 0.901 | 0.006 | 0.760 | 0.000 | Download |
ECFP2 fingerprints | 0.841 | 0.010 | 0.985 | 0.008 | 0.913 | 0.005 | 0.908 | 0.006 | 0.932 | 0.004 | 0.839 | 0.010 | Download |
ECFP4 fingerprints | 0.834 | 0.005 | 0.988 | 0.007 | 0.911 | 0.003 | 0.905 | 0.005 | 0.940 | 0.000 | 0.834 | 0.007 | Download |
ECFP6 fingerprints | 0.830 | 0.000 | 0.990 | 0.000 | 0.910 | 0.000 | 0.910 | 0.000 | 0.940 | 0.000 | 0.840 | 0.000 | Download |
Positive dataset | Negative dataset |
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