Target name

P48145: Neuropeptides B/W receptor type 1


  Protein function

Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.

  Database links

Uniprot primary ID P48145
PDB ID
DrugBank ID
BioGrid ID 109092
GuidetoPHARMACOLOGY ID 303
PharmGKB ID PA28912
KEGG ID hsa:2831
DIP ID
STRING ID 9606.ENSP00000330284
IntAct ID
DMDM 215274092
BRENDA
Reactome R-HSA-418594 R-HSA-375276
SignaLink
BioCyc
Entrez Gene (Gene ID) 2831
BindingDB P48145

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.730 0.000 0.990 0.000 0.860 0.000 0.840 0.000 0.919 0.003 0.760 0.000 Download
Estate fingerprints 0.739 0.003 0.867 0.007 0.803 0.005 0.791 0.003 0.845 0.005 0.614 0.007 Download
MACCS fingerprints 0.757 0.007 0.963 0.005 0.860 0.000 0.845 0.005 0.891 0.003 0.735 0.005 Download
Daylight fingerprints 0.730 0.000 0.990 0.000 0.860 0.000 0.840 0.000 0.901 0.006 0.760 0.000 Download
ECFP2 fingerprints 0.841 0.010 0.985 0.008 0.913 0.005 0.908 0.006 0.932 0.004 0.839 0.010 Download
ECFP4 fingerprints 0.834 0.005 0.988 0.007 0.911 0.003 0.905 0.005 0.940 0.000 0.834 0.007 Download
ECFP6 fingerprints 0.830 0.000 0.990 0.000 0.910 0.000 0.910 0.000 0.940 0.000 0.840 0.000 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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