Target name

P50052: Type-2 angiotensin II receptor


  Protein function

Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.

  Database links

Uniprot primary ID P50052
PDB ID
DrugBank ID DB01349
BioGrid ID 106692
GuidetoPHARMACOLOGY ID 35
PharmGKB ID PA44
KEGG ID hsa:186
DIP ID
STRING ID 9606.ENSP00000360973
IntAct ID P50052
DMDM 1703214
BRENDA
Reactome R-HSA-418594 R-HSA-375276
SignaLink
BioCyc
Entrez Gene (Gene ID) 186
BindingDB P50052

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.818 0.004 0.998 0.000 0.908 0.004 0.898 0.004 0.990 0.000 0.828 0.004 Download
Estate fingerprints 0.822 0.006 0.848 0.005 0.835 0.005 0.834 0.005 0.920 0.000 0.670 0.008 Download
MACCS fingerprints 0.776 0.005 0.872 0.003 0.824 0.005 0.816 0.005 0.920 0.000 0.651 0.007 Download
Daylight fingerprints 0.849 0.003 0.911 0.000 0.880 0.000 0.875 0.005 0.930 0.000 0.759 0.003 Download
ECFP2 fingerprints 0.919 0.006 0.981 0.000 0.950 0.000 0.947 0.005 0.990 0.000 0.903 0.005 Download
ECFP4 fingerprints 0.914 0.005 0.986 0.000 0.950 0.000 0.950 0.000 1.000 0.000 0.910 0.000 Download
ECFP6 fingerprints 0.887 0.005 0.993 0.000 0.940 0.000 0.938 0.004 1.000 0.000 0.885 0.005 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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