Target name

P50130: D(1A) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P50130
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID ssc:100144487
DIP ID
STRING ID 9823.ENSSSCP00000020447
IntAct ID
DMDM
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 100144487
BindingDB P50130

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.844 0.013 0.936 0.008 0.890 0.008 0.883 0.009 0.969 0.003 0.783 0.018 Download
Estate fingerprints 0.861 0.007 0.787 0.011 0.824 0.005 0.830 0.008 0.908 0.004 0.651 0.013 Download
MACCS fingerprints 0.938 0.004 0.758 0.006 0.848 0.004 0.861 0.003 0.940 0.000 0.708 0.006 Download
Daylight fingerprints 0.780 0.000 0.840 0.005 0.810 0.000 0.805 0.005 0.866 0.005 0.625 0.005 Download
ECFP2 fingerprints 0.977 0.005 0.921 0.005 0.949 0.003 0.952 0.004 0.990 0.000 0.904 0.008 Download
ECFP4 fingerprints 0.971 0.003 0.965 0.000 0.968 0.004 0.968 0.004 0.990 0.000 0.933 0.005 Download
ECFP6 fingerprints 0.954 0.005 0.974 0.000 0.964 0.005 0.964 0.005 0.990 0.000 0.930 0.005 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn